标签归档：influenza

Influenza HA (518-526)

发表于由

Influenza HA (518-526);

Influenza HA 518-526 是流感病毒血凝素 H-2Kd 限制性抗原表位，包含 533-541 个氨基酸序列。

Influenza HA (518-526)amp;;

Influenza HA (518-526) Chemical Structure

CAS No. : 186302-15-8

规格 是否有货
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250 mg ; 询价 ;
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生物活性

Influenza HA (518-526) is an H-2Kd-restricted epitope of the influenza virus hemagglutinin comprised amino acids 533 to 541[1].

分子量

940.05

Formula

C42H69N9O15
CAS 号

186302-15-8
Sequence

Ile-Tyr-Ser-Thr-Val-Ala-Ser-Ser-Leu
Sequence Shortening

IYSTVASSL
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. De Baets S, et al. Recombinant influenza virus carrying the respiratory syncytial virus (RSV) F85-93 CTL epitopereduces RSV replication in mice. J Virol. 2013 Mar;87(6):3314-23.

    [2]. Tamura M, et al. Definition of amino acid residues on the epitope responsible for recognition by influenza A virusH1-specific, H2-specific, and H1- and H2-cross-reactive murine cytotoxic T-lymphocyte clones. J Virol. 1998 Nov;72(11):9404-6.

Influenza HA (110-119)

发表于由

Influenza HA (110-119);

Influenza HA (110-119) 是流感病毒血凝素的 110-119 片段，可刺激 Treg 细胞增殖。

Influenza HA (110-119)amp;;

Influenza HA (110-119) Chemical Structure

CAS No. : 132031-50-6

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Influenza HA (110-119) is the 110-119 fragment of influenza virus hemagglutinin that can stimulate Treg cells proliferation[1][2].

分子量

1299.47

Formula

C63H90N14O16
CAS 号

132031-50-6
Sequence Shortening

SFERFEIFPK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. L Faulkner, et al. IL-2 linked to a peptide from influenza hemagglutinin enhances T cell activation by affecting the antigen-presentation function of bone marrow-derived dendritic cells. Int Immunol. 2001 Jun;13(6):713-21.

    [2]. Joseph Larkin 3rd, et al. Activation of CD4+ CD25+ regulatory T cell suppressor function by analogs of the selecting peptide. Eur J Immunol. 2007 Jan;37(1):139-46.

Influenza Matrix Protein (61-72)

发表于由

Influenza Matrix Protein (61-72);

Influenza Matrix Protein (61-72) 是衍生自流感病毒基质蛋白的多肽片段，对应于 61-72 氨基酸序列。Influenza Matrix Protein (61-72) 是一种特异性抗原决定簇，可以诱导 CD4+ T 细胞反应。

Influenza Matrix Protein (61-72)amp;;

Influenza Matrix Protein (61-72) Chemical Structure

CAS No. : 1286245-45-1

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Influenza Matrix Protein (61-72) is a peptide fragment derived from matrix protein of influenza viruses, corresponds to amino acids 61-72. Influenza Matrix Protein (61-72) is a specific epitope which can induce CD4+ T-cell response[1].

分子量

1352.60

Formula

C63H97N15O18
CAS 号

1286245-45-1
Sequence Shortening

GFVFTLTVPSER
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Linnemann T, et, al. Detection and quantification of CD4(+) T cells with specificity for a new major histocompatibility complex class II-restricted influenza A virus matrix protein epitope in peripheral blood of influenza patients. J Virol. 2000 Sep; 74(18): 8740-3.

CEF7, Influenza Virus NP (380-388)

发表于由

CEF7, Influenza Virus NP (380-388);

CEF7, Influenza Virus NP (380-388) 是一种 HLA-B*08 限制性流感病毒核蛋白表位。Influenza virus NP 在病毒和宿主细胞过程中起着关键的衔接分子的作用。

CEF7, Influenza Virus NP (380-388)amp;;

CEF7, Influenza Virus NP (380-388) Chemical Structure

CAS No. : 147100-46-7

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

CEF7, Influenza Virus NP (380-388) is a HLA-B*08 restricted influenza virus nucleoprotein epitope. Influenza virus NP functions as a key adapter molecule between virus and host cell processes[1][2].

分子量

1193.35

Formula

C55H84N16O14
CAS 号

147100-46-7
Sequence Shortening

ELRSRYWAI
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Portela A, et al. The influenza virus nucleoprotein: a multifunctional RNA-binding protein pivotal to virus replication. J Gen Virol. 2002 Apr;83(Pt 4):723-34.

    [2]. Boon AC, et al. The magnitude and specificity of influenza A virus-specific cytotoxic T-lymphocyte responses in humans is related to HLA-A and -B phenotype. J Virol. 2002 Jan;76(2):582-90.

Influenza NP (147-155) (TFA)

发表于由

Influenza NP (147-155) (TFA);

Influenza NP (147-155) TFA 是一种源于流感核蛋白的 Kd 限制性表位。

Influenza NP (147-155) (TFA)amp;;

Influenza NP (147-155) (TFA) Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Influenza NP (147-155) TFA is a Kd restricted epitope from influenza nucleoprotein[1].

分子量

1221.29

Formula

C50H83F3N16O16
Sequence

Thr-Tyr-Gln-Arg-Thr-Arg-Ala-Leu-Val
Sequence Shortening

TYQRTRALV
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Ikonomidis G, et al. Influenza-specific immunity induced by recombinant Listeria monocytogenes vaccines. Vaccine. 1997 Mar;15(4):433-40.

Influenza A NP(366-374) Strain A/PR/8/35

发表于由

Influenza A NP(366-374) Strain A/PR/8/35;

Influenza A NP(366-374) Strain A/PR/8/35 是源于流感病毒 (Influenza A/PR/8/35) 核蛋白的 H2-Db 限制性表位。

Influenza A NP(366-374) Strain A/PR/8/35amp;;

Influenza A NP(366-374) Strain A/PR/8/35 Chemical Structure

CAS No. : 132326-73-9

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Influenza A NP(366-374) Strain A/PR/8/35 is an H2-Db-restricted epitope from Influenza A/PR/8/35 nucleoprotein[1].

分子量

1026.10

Formula

C38H63N11O18S2
CAS 号

132326-73-9
Sequence Shortening

ASNENMETM
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Traboulsi H, et al. The Flavonoid Isoliquiritigenin Reduces Lung Inflammation and Mouse Morbidity during Influenza Virus Infection. Antimicrob Agents Chemother. 2015 Oct;59(10):6317-27.

Influenza NP (147-155)

发表于由

Influenza NP (147-155);

Influenza NP (147-155) 是一种源于流感核蛋白的 Kd 限制性表位。

Influenza NP (147-155)amp;;

Influenza NP (147-155) Chemical Structure

CAS No. : 132326-72-8

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Influenza NP (147-155) is a Kd restricted epitope from influenza nucleoprotein[1].

分子量

1107.26

Formula

C48H82N16O14
CAS 号

132326-72-8
Sequence

Thr-Tyr-Gln-Arg-Thr-Arg-Ala-Leu-Val
Sequence Shortening

TYQRTRALV
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Ikonomidis G, et al. Influenza-specific immunity induced by recombinant Listeria monocytogenes vaccines. Vaccine. 1997 Mar;15(4):433-40.

CEF1, Influenza Matrix Protein M1 (58-66)

发表于由

CEF1, Influenza Matrix Protein M1 (58-66);

CEF1, Influenza Matrix Protein M1 (58-66) 是源于甲型流感病毒 (influenza A virus) 的基质蛋白表位。

CEF1, Influenza Matrix Protein M1 (58-66)amp;;

CEF1, Influenza Matrix Protein M1 (58-66) Chemical Structure

CAS No. : 141368-69-6

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

CEF1, Influenza Matrix Protein M1 (58-66) is an epitope derived from the matrix protein of the influenza A virus[1].

分子量

966.17

Formula

C49H75N9O11
CAS 号

141368-69-6
Sequence

Gly-Ile-Leu-Gly-Phe-Val-Phe-Thr-Leu
Sequence Shortening

GILGFVFTL
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Petrova GV, et al. Cross-reactive responses to modified M1₅₈-₆₆ peptides by CD8⁺ T cells that use noncanonical BV genes can describe unknown repertoires. Eur J Immunol. 2012 Nov;42(11):3001-8.

Influenza HA (126-138)

发表于由

Influenza HA (126-138);

Influenza HA (126-138) 是流感病毒血凝素多肽，包含氨基酸 126-138 位点，能够诱导胸腺及周围 T 细胞的凋亡。

Influenza HA (126-138)amp;;

Influenza HA (126-138) Chemical Structure

CAS No. : 207349-63-1

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Influenza HA (126-138) is a influenza virus hemagglutinin (HA) peptide comprising amino acids 126-138, induces thymic and peripheral T-cell apoptosis[1].

分子量

1324.31

Formula

C52H81N19O22
CAS 号

207349-63-1
Sequence

His-Asn-Thr-Asn-Gly-Val-Thr-Ala-Ala-Ser-Ser-His-Glu
Sequence Shortening

HNTNGVTAASSHE
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Liblau RS, et al. Intravenous injection of soluble antigen induces thymic and peripheral T-cells apoptosis. Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):3031-6.

Influenza HA (307-319)

发表于由

Influenza HA (307-319);

Influenza HA (307-319) 是 Influenza HA 上的 307-319 氨基酸片段的 13 肽。Influenza HA 是流感病毒表面上的一种糖蛋白。

Influenza HA (307-319)amp;;

Influenza HA (307-319) Chemical Structure

CAS No. : 528526-85-4

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Influenza HA (307-319) is 13 amino acids 307 to 319 fragment of Influenza HA. Influenza HA is a glycoprotein found on the surface of influenza viruses[1].

分子量

1503.78

Formula

C69H118N18O19
CAS 号

528526-85-4
Sequence

Pro-Lys-Tyr-Val-Lys-Gln-Asn-Thr-Leu-Lys-Leu-Ala-Thr
Sequence Shortening

PKYVKQNTLKLAT
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Sriwilaijaroen N, et al. Molecular basis of the structure and function of H1 hemagglutinin of influenza virus. Proc Jpn Acad Ser B Phys Biol Sci. 2012;88(6):226-49.