Endothelin-1(ET-1) (22-38), Big(Human) 品牌：Anygen

发表于2024年2月11日由Whatman官网

Endothelin-1(ET-1) (22-38), Big(Human)

品牌：Anygen
CAS No.：
储存条件：-20℃
纯度：–

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
308-89631	–	0.5 mg	–	咨询	–	–

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* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Big Gastrin (Human) (Ammonium Form) 品牌：Peptide

发表于2024年1月30日由Whatman官网

Big Gastrin (Human) (Ammonium Form)

品牌：Peptide
CAS No.：
储存条件：-20℃
纯度：–

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
332-41831	–	0.1mg	–	咨询	–	–

* 干冰运输、大包装及大批量的产品需酌情添加运输费用

Big Endothelin-1 (1-38), human(Synonyms: 大内皮素-1 (1-38)，人)

发表于2024年1月18日由Whatman官网

Big Endothelin-1 (1-38), human;(Synonyms: 大内皮素-1 (1-38)，人)

Big Endothelin-1 (1-38), human 是内皮素-1 (endothelin-1) 的前体。Endothelin-1 (ET-1) 是一种有效的升压肽。

Big Endothelin-1 (1-38), humanamp;;(Synonyms: 大内皮素-1 (1-38)，人)

Big Endothelin-1 (1-38), human Chemical Structure

CAS No. : 120796-97-6

规格	价格	是否有货
1 mg	￥11500	询问价格货期

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生物活性

Big Endothelin-1 (1-38), human is the precursor of endothelin-1. Endothelin-1 (ET-1) is a potent vasopressor peptide^[1].

分子量

4282.92

Formula

C₁₈₉H₂₈₂N₄₈O₅₆S₅

CAS 号

120796-97-6

Sequence

Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-His-Val-Val-Pro-Tyr-Gly-Leu-Gly-Ser-Pro-Arg-Ser (Disulfide bridge: Cys1-Cys15; Cys3-Cys11)

Sequence Shortening

CSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGLGSPRS (Disulfide bridge: Cys1-Cys15; Cys3-Cys11)

中文名称

大内皮素-1 (1-38)，人

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-80deg;C	2 years
	-20deg;C	1 year
In solvent	-80deg;C	6 months
	-20deg;C	1 month

Solvent Solubility

In Vitro:;

H₂O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

;	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3.;;Recommended solution:

Overall charge of peptide	Details
Negative (lt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, add NH₄OH (lt;50 μL). 3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

参考文献

[1]. Marie-Hélène Fecteau, et al. Endothelin-1 (1-31) is an intermediate in the production of endothelin-1 after big endothelin-1 administration in vivo. Hypertension. 2005 Jul;46(1):87-92.