Secretoneurin, rat

Secretoneurin, rat;

Secretoneurin, rat 是由分泌粒蛋白 II (SgII) 的蛋白水解过程产生的一种 33 个氨基酸多肽。Secretoneurin, rat 在体内和体外诱导大鼠纹状体多巴胺释放,对单核细胞和嗜酸性粒细胞有很强的趋化作用,而对粒细胞则没有。

Secretoneurin, ratamp;;

Secretoneurin, rat Chemical Structure

CAS No. : 149146-12-3

规格 是否有货
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250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Secretoneurin, rat, a 33-amino acid polypeptide, is generated by proteolytic processing of secretogranin II (SgII). Secretoneurin, rat induces dopamine release in the rat striatum in vivo and in vitro, and it exerts a very strong chemotactic effect on monocytes and eosinophils but not on granulocytes[1].

分子量

3651.95

Formula

C159H252N40O58

CAS 号

149146-12-3

Sequence

Thr-Asn-Glu-Ile-Val-Glu-Glu-Gln-Tyr-Thr-Pro-Gln-Ser-Leu-Ala-Thr-Leu-Glu-Ser-Val-Phe-Gln-Glu-Leu-Gly-Lys-Leu-Thr-Gly-Pro-Ser-Asn-Gln

Sequence Shortening

TNEIVEEQYTPQSLATLESVFQELGKLTGPSNQ

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Troger J, et al. Secretoneurin in the peripheral ocular innervation. Invest Ophthalmol Vis Sci. 2005 Feb;46(2):647-54.

CTRP3 (rat) (rec.) (His) 品牌:Chimerigen


CTRP3 (rat) (rec.) (His)

品牌:Chimerigen
CAS No.:
储存条件:-20°C
纯度:>95% (SDS-PAGE)
产品编号

(生产商编号)

等级 规格 运输包装 零售价(RMB) 库存情况 参考值

CHI-RR-300CTRP3-C050

50 µg

CTRP3 (rat) (rec.) (His)                                                                品牌:Chimerigen

替代品:CHI-RR-300CTRP3-C010


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动,恕不另行通知,确切详情请联系上海金畔生物科技有限公司。

Activin-A (rat), (recombinant) 激活素A(大鼠),(重组) 品牌:Enzo


Activin-A (rat), (recombinant)

激活素A(大鼠),(重组)

品牌:Enzo
CAS No.:
储存条件:-80℃
纯度:
产品编号

(生产商编号)

等级 规格 运输包装 零售价(RMB) 库存情况 参考值

ENZ-PRT226-0100

100 ug

Activin-A (rat), (recombinant)                                                      激活素A(大鼠),(重组)            品牌:Enzo


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PAMP (Rat) PAMP (兔)电离质谱校准物 品牌:FUJIFILM Wako


PAMP (Rat)

PAMP (兔)电离质谱校准物

品牌:FUJIFILM Wako
CAS No.:
储存条件:-20℃
纯度:
产品编号

(生产商编号)

等级 规格 运输包装 零售价(RMB) 库存情况 参考值

166-24253

for Proteome Research 2 nmol×5本

PAMP (Rat)     PAMP (兔)电离质谱校准物            品牌:FUJIFILM Wako

替代品:352-41791


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IL-6Rbeta [GP130] (rat):Fc (human) (rec.) 品牌:Chimerigen


IL-6Rbeta [GP130] (rat):Fc (human) (rec.)

品牌:Chimerigen
CAS No.:
储存条件:-20°C
纯度:>98% (SDS-PAGE)
产品编号

(生产商编号)

等级 规格 运输包装 零售价(RMB) 库存情况 参考值

CHI-RF-311GP130-C050

50 µg

IL-6Rbeta [GP130] (rat):Fc (human) (rec.)                                                                品牌:Chimerigen


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* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动,恕不另行通知,确切详情请联系上海金畔生物科技有限公司。

Neuromedin S(rat)

Neuromedin S(rat);

Neuromedin S(rat) 是由 34 个氨基酸组成的肽段,来源于大鼠 Neuromedin S 。Neuromedin S 是从大鼠大脑分离出的神经肽,可以作为 FM4/TGR-1 的配体

Neuromedin S(rat)amp;;

Neuromedin S(rat) Chemical Structure

CAS No. : 843782-19-4

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Neuromedin S(rat) is a 34-amino acids peptide from rat Neuromedin S. Neuromedin S is a neuropeptide isolated from rat brain. Neuromedin S acts as a ligand for the G protein-coupled receptor FM4/TGR-1[1]

分子量

2642.97

Formula

C124H180N34O31

CAS 号

843782-19-4

Sequence Shortening

LPRLLHTDSRATIDFPKKDATIDFPKKDLFRPRN-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. E Vigo, et al. Neuromedin s as novel putative regulator of luteinizing hormone secretion. Endocrinology. 2007 Feb;148(2):813-23.

BigLEN(rat) TFA

BigLEN(rat) TFA;

BigLEN(rat)是一种有效的GPR171激动剂,其EC50 为1.6 nM。

BigLEN(rat) TFAamp;;

BigLEN(rat) TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

BigLEN(rat) is a potent GPR171 agonist with an EC50 of 1.6 nM[1].

IC50 Target

EC50: 1.6 nM (GPR171)[1]

体内研究
(In Vivo)

BigLEN-GPR171 system plays an important role in regulating feeding and metabolism in mice[1][2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1860.03

Formula

C78H129N24O25F3

Sequence

Leu-Glu-Asn-Ser-Ser-Pro-Gln-Ala-Pro-Ala-Arg-Arg-Leu-Leu-Pro-Pro

Sequence Shortening

LENSSPQAPARRLLPP

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. Gomes I, et al. GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding. Proc Natl Acad Sci U S A. 2013;110(40):16211-16216.

CART(55-102)(rat) TFA

CART(55-102)(rat) TFA;

CART(55-102)(rat) TFA 是一种具有强烈抑制食欲的鼠源饱腹感因子,与瘦素和神经肽 Y 密切相关,并可诱导焦虑和压力相关行为。

CART(55-102)(rat) TFAamp;;

CART(55-102)(rat) TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

CART(55-102)(rat) TFA is a rat satiety factor with potent appetite-suppressing activity. CART(55-102)(rat) TFA is closely associated with leptin and neuropeptide Y. CART(55-102)(rat) TFA can induces anxiety and stress-related behavior[1][2].

分子量

5373.20

Formula

C228H368F3N65O67S7

Sequence

Ile-Pro-Ile-Tyr-Glu-Lys-Lys-Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val-Arg-Lys-Gly-Ala-Arg-Ile-Gly-Lys-Leu-Cys-Asp-Cys-Pro-Arg-Gly-Thr-Ser-Cys-Asn-Ser-Phe-Leu-Leu-Lys-Cys-Leu (Disulfide bridge:Cys14-Cys32;Cys20-Cys40;Cys34-Cys47)

Sequence Shortening

IPIYEKKYGQVPMCDAGEQCAVRKGARIGKLCDCPRGTSCNSFLLKCL (Disulfide bridge:Cys14-Cys32;Cys20-Cys40;Cys34-Cys47)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. H Volkoff, et al. Effects of CART Peptides on Food Consumption, Feeding and Associated Behaviors in the Goldfish, Carassius Auratus: Actions on Neuropeptide Y- And Orexin A-induced Feeding. Brain Res. 2000 Dec 22;887(1):125-33.

    [2]. Shigeyuki Chaki, et al. Cocaine- And Amphetamine-Regulated Transcript Peptide Produces Anxiety-Like Behavior in Rodents. Eur J Pharmacol. 2003 Mar 7;464(1):49-54.

Neuropeptide S(Rat) TFA

Neuropeptide S(Rat) TFA;

Neuropeptide S(Rat) TFA is a potent endogenous neuropeptide S receptor (NSPR) agonist (EC50=3.2 nM). Neuropeptide S(Rat) TFA increases locomotor activity and wakefulness in mice. Neuropeptide S(Rat) TFA also reduces anxiety-like behavior in mice.

Neuropeptide S(Rat) TFAamp;;

Neuropeptide S(Rat) TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Neuropeptide S(Rat) TFA is a potent endogenous neuropeptide S receptor (NSPR) agonist (EC50=3.2 nM). Neuropeptide S(Rat) TFA increases locomotor activity and wakefulness in mice. Neuropeptide S(Rat) TFA also reduces anxiety-like behavior in mice.

分子量

2324.54

Formula

C97H161F3N34O29

Sequence Shortening

SFRNGVGSGVKKTSFRRAKQ

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Kisspeptin-10, rat

Kisspeptin-10, rat;

Kisspeptin-10, rat 是一种有效的血管收缩剂和血管生成抑制剂。Kisspeptin-10, rat 是亲吻蛋白受体 GPR54 (也叫 KISS1) 的配体。Kisspeptin-10 可降低 Methotrexate 诱导的生殖毒性,具有潜在的抗氧化活性。

Kisspeptin-10, ratamp;;

Kisspeptin-10, rat Chemical Structure

CAS No. : 478507-53-8

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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Kisspeptin-10, rat 的其他形式现货产品:

Kisspeptin-10, rat TFA

生物活性

Kisspeptin-10, rat is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, rat is a ligand for the rodent kisspeptin receptor (KISS1, GPR54). Kisspeptin-10 reduces Methotrexate-induced reproductive toxicity as a potential antioxidant compound[1].

IC50 Target

GPR54[1]
Angiogenesis[1]

分子量

1318.44

Formula

C63H83N17O15

CAS 号

478507-53-8

Sequence Shortening

YNWNSFGLRY-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. Güvenç M, et al. Ameliorating effect of kisspeptin-10 on methotrexate-induced sperm damages and testicular oxidative stress in rats. Andrologia. 2018 Oct;50(8):e13057.