荧光染料Vat Blue 2

荧光染料Dye Reagents Vat Blue 2;

Vat Blue 2 是一种靛蓝 (HY-N0335) 衍生物,是一种深蓝色的 5,5′-二溴-4,4′-二氯靛染料 (dye)。

Vat Blue 2

Vat Blue 2 Chemical Structure

CAS No. : 29245-44-1

规格 是否有货
5 mg 询价
10 mg 询价
100 mg 询价

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生物活性

Vat Blue 2, a indigo (HY-N0335) derivative, is a dark blue 5,5′-dibromo-4,4′-dichloroindigo dye[1].

体外研究
(In Vitro)

Indigo is the parent compound for a series of bromine and chlorine-substituted dyestuffs. Vat Blue 2 has four substituents, two each of chlorine and bromine, but located at different positions[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

488.95

Formula

C16H6Br2Cl2N2O2

CAS 号

29245-44-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Judy D. Timpa, et al. The Flammability of Cotton Fabrics Dyed with Indigo Dyes.

荧光染料Heptamethine cyanine dye-1(Synonyms: ADS 815EI)

荧光染料Dye Reagents Heptamethine cyanine dye-1;(Synonyms: ADS 815EI) 纯度: ge;96.0%

Heptamethine cyanine dye-1是一种用于生物系统荧光成像的近红外花青染料。

Heptamethine cyanine dye-1amp;;(Synonyms: ADS 815EI)

Heptamethine cyanine dye-1 Chemical Structure

CAS No. : 162411-29-2

规格 价格 是否有货 数量
10;mM;*;1 mL in DMSO ¥5692 In-stock
5 mg ¥3500 In-stock
10 mg ¥5000 In-stock
25 mg ¥10000 In-stock
50 mg ¥15000 In-stock
100 mg ¥21000 In-stock
200 mg ; 询价 ;
500 mg ; 询价 ;

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Heptamethine cyanine dye-1 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus

生物活性

Heptamethine cyanine dye-1 is a near-infrared cyanine dye for fluorescence imaging in biological systems.

分子量

739.17

Formula

C42H44ClIN2

CAS 号

162411-29-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, sealed storage, away from moisture and light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)

溶解性数据
In Vitro:;

DMSO : 50 mg/mL (67.64 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.3529 mL 6.7643 mL 13.5287 mL
5 mM 0.2706 mL 1.3529 mL 2.7057 mL
10 mM 0.1353 mL 0.6764 mL 1.3529 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂:;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.5 mg/mL (3.38 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (3.38 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

*以上所有助溶剂都可在 MCE 网站选购。

荧光染料NIR dye-1

荧光染料Dye Reagents NIR dye-1;

NIR dye-1 (Compound 1h) 是一种近红外 (NIR) 荧光染料。NIR dye-1 在 NIR 区域具有吸收和发射作用,同时保留了光学可调的羟基。

NIR dye-1

NIR dye-1 Chemical Structure

CAS No. : 1392488-07-1

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

NIR dye-1 (Compound 1h) is a near-infrared (NIR) fluorescent dye. NIR dye-1 has absorption and emission in the NIR region, while retaining an optically tunable hydroxyl group[1].

体外研究
(In Vitro)

To demonstrate the feasibility of developing water-soluble NIR dyes, NIR dye-1 (Compound 1h) is further synthesized, which bears several water-soluble groups. As expected, dye NIR dye-1 (Compound 1h) is soluble in pure PBS and newborn calf serum (without addition of any co-organic solvent) with a solubility of at least 2 mM in PBS and 3 mM in newborn calf serum[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

543.61

Formula

C26H25NO8S2

CAS 号

1392488-07-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Yuan L, et al. A unique approach to development of near-infrared fluorescent sensors for in vivo imaging. J Am Chem Soc. 2012 Aug 15;134(32):13510-23.

荧光染料Dye 993

荧光染料Dye Reagents Dye 993;

Dye 993为非对称的花青类染料,有选择渗透性,可用于检测电泳胶中的DNA。

Dye 993

Dye 993 Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Dye 993, substituted unsymmetrical cyanine dyes with selected permeability, useful in the detection of DNA in electrophoretic gels.

分子量

679.70

Formula

C34H42IN5S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

荧光染料Quinizarin(Synonyms: 1,4-二羟基蒽醌 1,4-Dihydroxyanthraquinone)

荧光染料Dye Reagents Quinizarin;(Synonyms: 1,4-二羟基蒽醌; 1,4-Dihydroxyanthraquinone) 纯度: ge;95.0%

Quinizarin (1,4-Dihydroxyanthraquinone) 是 Doxorubicin、Daunorubicin、Adriamycin 等抗癌药物的一部分,通过插入方式与 DNA 相互作用 (Kd=86.1 μM)。Quinizarin 是一种杀菌剂和杀虫剂,并已显示出抑制肿瘤细胞生长的能力。

Quinizarinamp;;(Synonyms: 1,4-二羟基蒽醌; 1,4-Dihydroxyanthraquinone)

Quinizarin Chemical Structure

CAS No. : 81-64-1

规格 价格 是否有货 数量
10;mM;*;1 mL in DMSO ¥550 In-stock
1 g ¥500 In-stock
5 g ; 询价 ;
10 g ; 询价 ;

* Please select Quantity before adding items.

Quinizarin 相关产品

bull;相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Anti-Infection Compound Library
  • Cell Cycle/DNA Damage Compound Library
  • Natural Product Library
  • Anti-Cancer Compound Library
  • Anti-Aging Compound Library
  • Antifungal Compound Library
  • Phenols Library
  • Traditional Chinese Medicine Monomer Library

生物活性

Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (Kd=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth[1][2].

体外研究
(In Vitro)

1,4-Dihydroxyanthraquinone (1,4-DHAQ, a fluorophore) doped cellulose (CL) (denoted as 1,4-DHAQ@CL) microporous nanofiber film has been achieved via simple electrospinning and subsequent deacetylating, and used for highly sensitive and selective fluorescence detection of Cu(2+) in aqueous solution[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

240.21

Formula

C14H8O4

CAS 号

81-64-1

中文名称

1,4-二羟基蒽醌;醌茜

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

DMSO : 3.33 mg/mL (13.86 mM; ultrasonic and warming and heat to 60°C)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.1630 mL 20.8151 mL 41.6302 mL
5 mM 0.8326 mL 4.1630 mL 8.3260 mL
10 mM 0.4163 mL 2.0815 mL 4.1630 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Verebová V, et al. Anthraquinones quinizarin and danthron unwind negatively supercoiled DNA and lengthen linear DNA. Biochem Biophys Res Commun. 2014;444(1):50-55.

    [2]. Dominic Cheuk, et al. Investigation into solid and solution properties of quinizarin.

    [3]. Wang M, et al. Electrospun 1,4-DHAQ-doped cellulose nanofiber films for reusable fluorescence detection of trace Cu2+ and further for Cr3+. Environ Sci Technol. 2012;46(1):367-373.

荧光染料Dye 937

荧光染料Dye Reagents Dye 937;

Dye 937为非对称的花青类染料,有选择渗透性,可用于检测电泳胶中的DNA。

Dye 937

Dye 937 Chemical Structure

CAS No. : 195199-04-3

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Dye 937, substituted unsymmetrical cyanine dyes with selected permeability, useful in the detection of DNA in electrophoretic gels.

分子量

636.63

Formula

C32H37IN4S

CAS 号

195199-04-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Endoplasmic reticulum dye 1

Endoplasmic reticulum dye 1;

Endoplasmic reticulum dye 1 是一种活细胞显像剂 (live cell imaging agent),用于检测质膜上的胞外活动。Endoplasmic reticulum dye 1 具有低细胞毒性,耐光漂白,是短期或长期成像的理想选择。

Endoplasmic reticulum dye 1amp;;

Endoplasmic reticulum dye 1 Chemical Structure

CAS No. : 1404104-40-0

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Endoplasmic reticulum dye 1 is a promising live cell imaging agent for the detection of exocytotic events at the plasma membrane. Endoplasmic reticulum dye 1 shows low cytotoxicity, resistance to photobleaching , which is ideal for imaging either short- or long-time courses[1].

分子量

596.57

Formula

C21H12N7O3Re

CAS 号

1404104-40-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Christie A Bader, et al. Imaging nuclear, endoplasmic reticulum and plasma membrane events in real time. FEBS Lett. 2016 Sep;590(18):3051-60.

D149 Dye(Synonyms: D149 Indoline dye D149)

D149 Dye;(Synonyms: D149; Indoline dye D149) 纯度: ge;95.0%

D149 Dye 是一种二氢吲哚类染料,是一种具有高消光系数的非金属有机敏化剂。

D149 Dyeamp;;(Synonyms: D149;  Indoline dye D149)

D149 Dye Chemical Structure

CAS No. : 786643-20-7

规格 价格 是否有货 数量
50 mg ¥1800 In-stock
100 mg ¥2930 In-stock
500 mg ¥5800 In-stock
1 g ; 询价 ;
5 g ; 询价 ;

* Please select Quantity before adding items.

D149 Dye 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus

生物活性

D149 Dye is an indoline-based dye, which is a high-extinction-coefficient metal-free organic sensitizer.

体外研究
(In Vitro)

D149 is a metal-free organic dye, which is promising all-organic alternatives. D149 displays power conversion efficiency of up to 9%. Furthermore, D149 has a peak extinction co-efficient of 68700 M-1 cm-1 at 540 nm, significantly higher than 13900 M-1cm-1 at 535 nm for N719[1]. D149, a metal-free indoline dye, is one of the most promising sensitizers for dye-sensitized solar cells (DSSCs) and has shown very high solar energy conversion efficiencies of 9%. D149 shows a large number of unresolved aromatic and olefinic signals between 7 and 7.5 ppm[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

741.94

Formula

C42H35N3O4S3

CAS 号

786643-20-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, protect from light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)

溶解性数据
In Vitro:;

DMSO : 1 mg/mL (1.35 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.3478 mL 6.7391 mL 13.4782 mL
5 mM
10 mM

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Lin J, et al. 3D hierarchical rutile TiO2 and metal-free organic sensitizer producing dye-sensitized solar cells 8.6% conversion efficiency. Sci Rep. 2014 Aug 29;4:5769.

    [2]. El-Zohry A, et al. Isomerization and Aggregation of the Solar Cell Dye D149. J Phys Chem C Nanomater Interfaces. 2012 Dec 20;116(50):26144-26153.

Cell Assay
[1]

The porous TiO2 films are immersed in a 0.5 mM D149 (1-material) dye solution in a 1:1 (v/v) mixture of acetonitrile (HPLC) and tert-butanol (LR) overnight once their temperature decreased to approximately 110°C. The samples are then taken out of the dye bath, washed with acetonitrile, and dried. The working electrode and Pt counter electrode [produced using a pre-drilled piece of 2.3 mm FTO glass, coated with one drop of 10 mM platinic acid solution [H2PtCl6] and heated to 400°C for 20 min] are assembled into a sandwich type cell and sealed with a spacer of 25 μm Surlyn. An I-1/I3-1 organic solvent based electrolyte solution [50 mM iodine, 0.6 M 1,2-dimethyl-3-propylimidazelium iodide, 0.1 M lithium iodide in methoxypropionitrile] is introduced via vacuum back-filling. The hole is sealed with a piece of aluminium foil-backed Surlyn[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献
  • [1]. Lin J, et al. 3D hierarchical rutile TiO2 and metal-free organic sensitizer producing dye-sensitized solar cells 8.6% conversion efficiency. Sci Rep. 2014 Aug 29;4:5769.

    [2]. El-Zohry A, et al. Isomerization and Aggregation of the Solar Cell Dye D149. J Phys Chem C Nanomater Interfaces. 2012 Dec 20;116(50):26144-26153.

DASPEI

DASPEI;

DASPEI 是一种荧光染料。DASPEI 是一种苯乙烯基染料,可对活细胞的线粒体染色。 DASPEI 荧光探针的斯托克斯位移较大,且膜电位相对缓慢地吸收。

DASPEIamp;;

DASPEI Chemical Structure

CAS No. : 3785-01-1

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

DASPEI is a fluorescent dye. DASPEI is a styryl dye that stains mitochondria of live cells. DASPEI has a large fluorescence Stokes shift and is taken up relatively slowly as a function of membrane potential[1].

分子量

380.27

Formula

C17H21IN2

CAS 号

3785-01-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. E M Leise. Selective retention of the fluorescent dye DASPEI in a larval gastropod mollusc after paraformaldehyde fixation. Microsc Res Tech. 1996 Apr 15;33(6):496-500.

DNA-Dye NonTox|EB替代物高灵敏度核酸染料

DNA-Dye NonTox来自德国著名生化试剂生产商AppliChem,以非整合性方式与DNA双链结合,DNA-Dye NonTox是一款无毒害、非诱变性、高灵敏度的核酸染料,在使用过程中无需特殊保护措施,废弃物可直接倒入下水道,DNA-Dye NonTox对环境也不会有任何影响。

DNA-Dye NonTox以即用型6X Loading Buffer形式提供,在使用时只需按1:5比例与样品混合10秒钟即可点样,后续无需任何染色步骤,包含3种指示剂:溴酚蓝、二甲苯蓝、橙黄G,电泳后便可直接观察,而且DNA-Dye NonTox与EB有相同的光谱特性,因此用它替代EB时不需要更换成像系统。

DNA-Dye NonTox 产品特点:
1. 无毒害 (LC>5000mg/kg),并对环境无任何影响;
2. 不对样品DNA产生任何突变影响,经过Ames测试,对样品的影响与PBS等同;
3. 高灵敏度(5-10ng);
4. 使用方便:即用型6X Loading Buffer,不再需要任何染色步骤;
5. 背景低
6. 可以用于胶回收并不影响样品质量;

DNA-Dye NonTox与市场上其他产品比较

参数

DNA-Dye NonTox

EB

SYBR Green

GenGreen

Gelred

Goldview

安全性

无诱变性

高诱变性

剂量达到1μg/plate 时,致突变

诱变性比EB低

在 18.5 μg /mL S9代谢活化时有微弱的诱变性

高诱变性

灵敏度

++++

++++

+++

++++

++++

++

稳定性

+++++

++++

++++

++++

+++++

++++

背景

对核酸迁移影响

相对较大

相对较低

是否需要再加

Loading Buffer

无需

需要

需要

需要

需要

需要

是否需要染色步骤

无需

需要

需要

需要

需要

需要

DNA-Dye NonTox产品信息

品牌

货号

品名

规格

德国AppliChem

A9555

DNA-Dye NonTox

1ml

DNA-Dye NonTox保存:2-8°C避光保存
DNA-Dye NonTox有效期:12个月

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