D-(+)-Melezitose hydrate(Synonyms: (+)-Melezitose hydrate; D-Melezitose hydrate)

天然产物 糖类和糖苷 Saccharides and Glycosides

D-(+)-Melezitose hydrate;(Synonyms: (+)-Melezitose hydrate; D-Melezitose hydrate) 纯度: ge;98.0%

D-(+)-Melezitose hydrate ((+)-Melezitose hydrate) 可用于鉴定吲哚阳性和吲哚阴性克雷伯菌属 (Klebsiella spp) 的临床分离株。

D-(+)-Melezitose hydrate(Synonyms: (+)-Melezitose hydrate; D-Melezitose hydrate)

D-(+)-Melezitose hydrate Chemical Structure

CAS No. : 207511-10-2

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D-(+)-Melezitose hydrate 相关产品

bull;相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus

生物活性

D-(+)-Melezitose hydrate ((+)-Melezitose hydrate) can be used to identify clinical isolates of indole-positive and indole-negative Klebsiella spp[1].

Formula

C18H32O16.xH2O

CAS 号

207511-10-2

中文名称

D-(+) 松三糖(水合物)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
参考文献
  • [1]. Alves MS, et al. Identification of clinical isolates of indole-positive and indole-negative Klebsiella spp. J Clin Microbiol. 2006 Oct;44(10):3640-6. Epub 2006 Aug 23.

Stachyose hydrate(Synonyms: 水苏糖)

天然产物 糖类和糖苷 Saccharides and Glycosides

Stachyose hydrate;(Synonyms: 水苏糖)

Stachyose hydrate 作为一种益生元,可增强有益细菌的生长和活性。Stachyose hydrate具有降血糖作用的,并可用过调节肠道微生物改善炎症。

Stachyose hydrate(Synonyms: 水苏糖)

Stachyose hydrate Chemical Structure

CAS No. : 54261-98-2

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生物活性

Stachyose hydrate act as a prebiotic to enhance the growth and activity of beneficial bacteria. Stachyose hydrate exhibit a hypoglycemic effect, and improve inflammation through modulating gut microbiota[1].

IC50 Target

Human Endogenous Metabolite

;

Formula

C24H42O21.xH2O

CAS 号

54261-98-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Cai-Na Li, et al. Berberine combined with stachyose induces better glycometabolism than berberine alone through modulating gut microbiota and fecal metabolomics in diabetic mice. Phytother Res. 2020 May;34(5):1166-1174.

Colistin A sulfate hydrate

Colistin A sulfate hydrate;

Colistin A sulfate hydrate 是 Colistin 的一种主要成分。Colistin 是一种多粘菌素抗生素 (antibiotic)。Colistin 可用来对抗由革兰氏阴性菌引起的感染。

Colistin A sulfate hydrateamp;;

Colistin A sulfate hydrate Chemical Structure

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生物活性

Colistin A sulfate hydrate is a major component of Colistin. Colistin is a polymyxin antibiotic and can be used to combat infections caused by problematic gram-negative bacteria[1].

分子量

1285.55

Formula

C53H104N16O18S

Sequence

{Dab}-Thr-{Dab}-{Dab}-{Dab}-{D-Leu}-Leu-{Dab}-{Dab}-Thr (Lactam bridge:Dab-4-Thr-10)

Sequence Shortening

{Dab}T{Dab}{Dab}{Dab}{D-Leu}L{Dab}{Dab}T (Lactam bridge:Dab-4-Thr-10)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. Lauren M. Lim, et al. Resurgence of Colistin: A Review of Resistance, Toxicity, Pharmacodynamics, and Dosing. Pharmacotherapy. 2010 Dec; 30(12): 1279-1291.

(+)-Catechin hydrate(Synonyms: (+)-水合儿茶素)

天然产物 黄酮类 Flavonoids

(+)-Catechin hydrate (Synonyms: (+)-水合儿茶素) 纯度: 99.59%

(+)-Catechin hydrate 抑制环加氧酶-1 (COX-1) , IC50 为 1.4 μM。

(+)-Catechin hydrate(Synonyms: (+)-水合儿茶素)

(+)-Catechin hydrate Chemical Structure

CAS No. : 225937-10-0

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500 mg   询价  

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(+)-Catechin hydrate 相关产品

相关化合物库:

  • Natural Product Library Plus
  • Drug Repurposing Compound Library Plus
  • Clinical Compound Library Plus
  • Bioactive Compound Library Plus
  • Immunology/Inflammation Compound Library
  • Natural Product Library
  • Anti-Cancer Compound Library
  • Clinical Compound Library
  • Anti-Aging Compound Library
  • Drug Repurposing Compound Library
  • Diabetes Related Compound Library
  • Anti-COVID-19 Compound Library
  • Traditional Chinese Medicine Monomer Library
  • Flavonoids Library
  • Food-Sourced Compound Library

生物活性

(+)-Catechin hydrate inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.

IC50 & Target[1]

COX-1

1.4 μM (IC50)

体外研究
(In Vitro)

(+)-Catechin exhibits >95% inhibitory activity at 70 μg/mL against cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM[1]. A dose-dependent reduction in color is observed after 24 hours of treatment with (+)-Catechin, and 54.76% of the cells are dead at the highest concentration of (+)-Catechin tested (160 μg/mL) whereas the IC50 of (+)-Catechin is achieved at 127.62 μg/mL (+)-Catechin. A dose- and time-dependent increase in the induction of apoptosis is observed when MCF-7 cells are treated with (+)-Catechin. When compare to the control cells at 24 hours, 40.7 and 41.16% of the cells treated with 150 μg/mL and 300 μg/mL (+)-Catechin, respectively, undergo apoptosis. The expression levels of Caspase-3, -8, and -9 and p53 in MCF-7 cells treated with 150 μg/mL (+)-Catechin for 24 h increase by 5.81, 1.42, 3.29, and 2.68 fold, respectively, as compare to the levels in untreated control cells[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Animals treated with (+)-Catechin at the lowest tested dose, i.e., 50 mg/kg, p.o. have spent comparatively more time in exploring the novel object in the choice trial, however, the difference is not statistically significant. (+)-Catechin prevents the time-induced episodic memory deficits in a dose-dependent manner, the most effective being 200 mg/kg, p.o.. Treatment with (+)-Catechin prevents the rise in MPO level compare to DOX alone treatment group (21.98±9.44 and 36.76±4.39% in the hippocampus and the frontal cortex respectively)[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

Formula

C15H14O6.xH2O

CAS 号

225937-10-0

中文名称

(+)-水合儿茶素

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

DMSO : 50 mg/mL (Need ultrasonic)

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂: 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (Infinity mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (Infinity mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂: 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (Infinity mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (Infinity mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中,混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中,再用生理盐水定容至 10 mL,完全溶解,澄清透明
  • 3.

    请依序添加每种溶剂: 10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (Infinity mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (Infinity mM,饱和度未知) 的澄清溶液,此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中,混合均匀。

*以上所有助溶剂都可在 Shanghai Jinpan Biotech Co Ltd 网站选购。
参考文献
  • [1]. Waffo-Téguo P, et al. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutr Cancer. 2001;40(2):173-9.

    [2]. Alshatwi AA. Catechin hydrate suppresses MCF-7 proliferation through TP53/Caspase-mediated apoptosis. J Exp Clin Cancer Res. 2010 Dec 17;29:167.

    [3]. Cheruku SP, et al. Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats. Cytotechnology. 2018 Feb;70(1):245-259.

Cell Assay
[2]

The Cell viability assay is performed to assess the toxicity of different concentrations of (+)-Catechin on MCF-7 cells. Briefly, MCF-7 cells (2×104 cells/well) are plated in 96-well plates and treated with 0 μg/mL (+)-Catechin and 160 μg/mL (+)-Catechin for 24 hours. Then, 40 μL of the Cell Titer Blue solution is directly added to the wells and incubated at 37°C for 6 hours. The fluorescence is recorded with a 560 nm/590 nm (excitation/emission) filter set using a microplate fluorescence reader, and the IC50 is calculated. Quadruplet samples are run for each concentration of (+)-Catechin in three independent experiments[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Administration
[3]

Rats[3]
Twelve weeks old, healthy male rats weighing 200 to 230 g are used in this study. Rats are divided into four experimental groups (n=9 each) for one vehicle and three groups of (+)-Catechin (three doses). The doses of (+)-Catechin are prepared at 50, 100, 200 mg/kg and administered orally for 7 days prior to and during the experimental trials. Episodic memory, the conscious memory of the past experiences is evaluated in this study[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献
  • [1]. Waffo-Téguo P, et al. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutr Cancer. 2001;40(2):173-9.

    [2]. Alshatwi AA. Catechin hydrate suppresses MCF-7 proliferation through TP53/Caspase-mediated apoptosis. J Exp Clin Cancer Res. 2010 Dec 17;29:167.

    [3]. Cheruku SP, et al. Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats. Cytotechnology. 2018 Feb;70(1):245-259.

Rutin hydrate(Synonyms: Rutoside hydrate; Quercetin 3-O-rutinoside hydrate)

天然产物 糖类和糖苷 Saccharides and Glycosides

Rutin hydrate;(Synonyms: Rutoside hydrate; Quercetin 3-O-rutinoside hydrate) 纯度: ge;98.0%

Rutin (Rutoside) hydrate 是一种广泛存在于多种植物中的黄酮类化合物,具有抗炎、降糖、抗氧化、神经保护、肾脏保护、肝脏保护和降低 Aβ 低聚物活性等多种生物活性。Rutin hydrate 能穿过血脑屏障。Rutin hydrate 通过抑制细胞凋亡、线粒体功能紊乱和氧化应激抑制万古霉素诱导的肾小管细胞凋亡。

Rutin hydrate(Synonyms: Rutoside hydrate; Quercetin 3-O-rutinoside hydrate)

Rutin hydrate Chemical Structure

CAS No. : 207671-50-9

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Free Sample (0.1-0.5 mg) ; Apply now ;
500 mg ¥400 In-stock
1 g ; 询价 ;
5 g ; 询价 ;

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Rutin hydrate 相关产品

bull;相关化合物库:

  • Natural Product Library Plus
  • Drug Repurposing Compound Library Plus
  • FDA-Approved Drug Library Plus
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生物活性

Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin hydrate can cross the blood brain barrier. Rutin hydrate attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress[1][2][3].

体内研究
(In Vivo)

Rutin hydrate ameliorates cadmium chloride-induced spatial memory loss and neural apoptosis in rats by enhancing levels of acetylcholine, inhibiting JNK and ERK1/2 activation and activating mTOR signaling[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

分子量

740.26

Formula

C27H32O17

CAS 号

207671-50-9

中文名称

芸香苷水合物;紫皮甙水合物;维生素 P 水合物;芦丁水合物

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, protect from light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)

溶解性数据
In Vitro:;

DMSO : 50 mg/mL (67.54 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.3509 mL 6.7544 mL 13.5088 mL
5 mM 0.2702 mL 1.3509 mL 2.7018 mL
10 mM 0.1351 mL 0.6754 mL 1.3509 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂:;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.5 mg/mL (3.38 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (3.38 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂:;10% DMSO ;; 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (3.38 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (3.38 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中,混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中,再用生理盐水定容至 10 mL,完全溶解,澄清透明
  • 3.

    请依序添加每种溶剂:;10% DMSO ;; 90% corn oil

    Solubility: ≥ 2.5 mg/mL (3.38 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (3.38 mM,饱和度未知) 的澄清溶液,此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中,混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。
参考文献
  • [1]. Ghorbani A. Mechanisms of antidiabetic effects of flavonoid rutin. Biomed Pharmacother. 2017;96:305-312.

    [2]. Habtemariam S. Rutin as a Natural Therapy for Alzheimer’s Disease: Insights into its Mechanisms of Action. Curr Med Chem. 2016;23(9):860-873.

    [3]. Xu PX, et al. Rutin improves spatial memory in Alzheimer’s disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation. Behav Brain Res. 2014;264:173-180.

    [4]. Abdel-Aleem GA, et al. Rutin hydrate ameliorates cadmium chloride-induced spatial memory loss and neural apoptosis in rats by enhancing levels of acetylcholine, inhibiting JNK and ERK1/2 activation and activating mTOR signalling. Arch Physiol Biochem. 2018;124(4):367-377.

Animal Administration
[1]

Rats[1]
(1) A control group receives of 0.01 g/mL carboxymethylcellulose (CMC) dissolved in distilled water; (2) α-tocopherol acetate treated group: control rats receive α-tocopherol (120 IU/rat) diluted in 0.1 mL of coconut oil; (3) Rutin hydrate treated control group (control + Rutin hydrate): control rats receive Rutin hydrate (100 mg/kg); (4) CdCl2 intoxicated group receives CdCl2 at a final dose of 5 mg/kg to induce neurotoxicity; (5) CdCl2 + Rutin hydrate treated group (CdCl2 + Rutin hydrate) receives CdCl2 (5 mg/kg) and receives a coincided dose of Rutin hydrate (100 mg/kg body weight); (6) CdCl2 + Rutin hydrate + α-tocopherol acetate-treated group receives CdCl2 (5 mg/kg) and receives concomitant dose of Rutin hydrate (100 mg/kg) in conjugation with α-tocopherol acetate (120 IU/rat) that is diluted in 0.1 mL of coconut oil. All treatments are given by orogastric gavage with a polyethylene catheter PE 190 daily for 30 days[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献
  • [1]. Ghorbani A. Mechanisms of antidiabetic effects of flavonoid rutin. Biomed Pharmacother. 2017;96:305-312.

    [2]. Habtemariam S. Rutin as a Natural Therapy for Alzheimer’s Disease: Insights into its Mechanisms of Action. Curr Med Chem. 2016;23(9):860-873.

    [3]. Xu PX, et al. Rutin improves spatial memory in Alzheimer’s disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation. Behav Brain Res. 2014;264:173-180.

    [4]. Abdel-Aleem GA, et al. Rutin hydrate ameliorates cadmium chloride-induced spatial memory loss and neural apoptosis in rats by enhancing levels of acetylcholine, inhibiting JNK and ERK1/2 activation and activating mTOR signalling. Arch Physiol Biochem. 2018;124(4):367-377.

Oxypeucedanin hydrate(Synonyms: (+)-Oxypeucedanin hydrate)

天然产物 天然产物苯丙素类 Phenylpropanoids

Oxypeucedanin hydrate (Synonyms: (+)-Oxypeucedanin hydrate)

Oxypeucedanin hydrate ((+)-Oxypeucedanin hydrate) 是从 D. anethifolia 中分离出的一种天然产物。 Prangol 对成纤维细胞和母淋巴瘤细胞有轻微毒性。

Oxypeucedanin hydrate(Synonyms: (+)-Oxypeucedanin hydrate)

Oxypeucedanin hydrate Chemical Structure

CAS No. : 2643-85-8

规格 价格 是否有货 数量
5 mg ¥1300 In-stock
10 mg ¥2000 In-stock
25 mg ¥4100 In-stock
50 mg ¥6500 In-stock
100 mg   询价  
200 mg   询价  

* Please select Quantity before adding items.

Oxypeucedanin hydrate 相关产品

相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Natural Product Library
  • Anti-Cancer Compound Library
  • Anti-Blood Cancer Compound Library

生物活性

Oxypeucedanin hydrate ((+)-Oxypeucedanin hydrate) is a natural product isolated from D. anethifolia. Prangol exhibits mild toxicity on fibroblasts and parental lymphoma cells[1].

分子量

304.29

Formula

C16H16O6

CAS 号

2643-85-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Mottaghipisheh J, et al. Antiproliferative and cytotoxic activities of furocoumarins of Ducrosia anethifolia. Pharm Biol. 2018 Dec;56(1):658-664.

(-)-Oxypeucedanin hydrate(Synonyms: (-)-Prangol)

天然产物 天然产物苯丙素类 Phenylpropanoids

(-)-Oxypeucedanin hydrate (Synonyms: (-)-Prangol)

(-)-Oxypeucedanin hydrate ((-)-Prangol) 是从 Ducrosia anethifolia 中分离得到的呋喃香豆素衍生物。

(-)-Oxypeucedanin hydrate(Synonyms: (-)-Prangol)

(-)-Oxypeucedanin hydrate Chemical Structure

CAS No. : 133164-11-1

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生物活性

(-)-Oxypeucedanin hydrate ((-)-Prangol) is a derivative of furocoumarin isolated from Ducrosia anethifolia[1].

体外研究
(In Vitro)

D. anethifolia furocoumarin shows antiproliferative and cytotoxic activities[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

304.29

Formula

C16H16O6

CAS 号

133164-11-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Mottaghipisheh J, et al. Antiproliferative and cytotoxic activities of furocoumarins of Ducrosia anethifolia. Pharm Biol. 2018;56(1):658-664.

Osthol hydrate(Synonyms: 水合蛇床子素)

天然产物 天然产物苯丙素类 Phenylpropanoids

Osthol hydrate (Synonyms: 水合蛇床子素)

Osthol hydrate 是从 F. schottiana 中分离出的一种天然产物。

Osthol hydrate(Synonyms: 水合蛇床子素)

Osthol hydrate Chemical Structure

CAS No. : 69219-24-5

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生物活性

Osthol hydrate is a natural product isolated from F. schottiana[1].

分子量

262.30

Formula

C15H18O4

CAS 号

69219-24-5

中文名称

水合蛇床子素

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Hollis, A., et al. The Chemical Constituents of Australian Flindersia Species. XIV. The Constituents of Flindersia pubescens Bail. And F. schottiana F. Muell. Australian Journal of Chemistry, 1961;14(1), 100.

4-Methylumbelliferyl-β-D-glucuronide hydrate(Synonyms: MUG)

4-Methylumbelliferyl-β-D-glucuronide hydrate;(Synonyms: MUG) 纯度: 99.98%

4-Methylumbelliferyl-β-D-glucuronide hydrate 是一种荧光底物 (λex=362 nm,λem=445 nm)。

4-Methylumbelliferyl-β-D-glucuronide hydrateamp;;(Synonyms: MUG)

4-Methylumbelliferyl-β-D-glucuronide hydrate Chemical Structure

CAS No. : 881005-91-0

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Free Sample (0.1-0.5 mg) ; Apply now ;
10;mM;*;1 mL in DMSO ¥790 In-stock
25 mg ¥600 In-stock
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4-Methylumbelliferyl-beta;-D-glucuronide hydrate 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Glycoside Compound Library

生物活性

4-Methylumbelliferyl-β-D-glucuronide hydrate is a fluorogenic substrat (λex=362 nm , λem=445 nm).

体外研究
(In Vitro)

4-Methylumbelliferyl-β-D-glucuronide hydrate is a fluorogenic substrat with λex=362 nm and λem=445 nm. The half-saturation constants, Km, that are calculated for sewage samples are close to the Km values calculated based on experimental plots presented previously for freshwaters[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

370.31

Formula

C16H18O10

CAS 号

881005-91-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, protect from light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)

溶解性数据
In Vitro:;

DMSO : 150 mg/mL (405.07 mM; Need ultrasonic)

H2O : 5.2 mg/mL (14.04 mM; Need ultrasonic and warming)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.7004 mL 13.5022 mL 27.0044 mL
5 mM 0.5401 mL 2.7004 mL 5.4009 mL
10 mM 0.2700 mL 1.3502 mL 2.7004 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. George I, et al. Use of beta-D-galactosidase and beta-D-glucuronidase activities for quantitative detection of totaland fecal coliforms in wastewater. Can J Microbiol. 2001 Jul;47(7):670-5.

Kinase Assay
[1]

GLUase activity of E. coli cells is measured. Three millilitres of 4-Methylumbelliferyl-β-D-glucuronide hydrate (MUGlu) solution (55 mg of hydrated MUGlu and 20 mL of Triton X-100 in 50 mL of sterile water) is added to each flask (final concentration:165 mg/L). The incubation temperature is 44°C. One hundred microlitres of 2 M NaOH solution is added to each 2.9-mL aliquot to obtain a pH>10 before the fluorescence measurement[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献
  • [1]. George I, et al. Use of beta-D-galactosidase and beta-D-glucuronidase activities for quantitative detection of totaland fecal coliforms in wastewater. Can J Microbiol. 2001 Jul;47(7):670-5.

Sinigrin hydrate(Synonyms: 黑芥子硫苷酸钾一水;芥子甙单水合物)

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Sinigrin hydrate (Synonyms: 黑芥子硫苷酸钾一水;芥子甙单水合物)

Sinigrin (hydrate) 是十字花科植物中存在的天然脂肪族芥子油苷。Sinigrin (hydrate) 具有抗癌,抗菌,抗真菌,抗氧化和消炎的作用。

Sinigrin hydrate(Synonyms: 黑芥子硫苷酸钾一水;芥子甙单水合物)

Sinigrin hydrate Chemical Structure

CAS No. : 64550-88-5

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生物活性

Sinigrin (hydrate) is a natural aliphatic glucosinolate present in plants of the Brassicaceae family. Sinigrin (hydrate) exhibits anti-cancer, antibacterial, antifungal, antioxidant and anti-inflammatory activities[1].

分子量

415.48

Formula

C10H18KNO10S2

CAS 号

64550-88-5

中文名称

黑芥子硫苷酸钾一水;芥子甙单水合物

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Mazumder A, et, al. Sinigrin and Its Therapeutic Benefits. Molecules. 2016 Mar 29;21(4):416.