标签归档：chloride

Petunidin-3-O-glucoside chloride

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

Petunidin-3-O-glucoside chloride;

Petunidin-3-O-glucoside chloride 是从菜心种子中分离得到的一种黄酮类化合物，具有抗氧化 (antioxidant) 活性。

Petunidin-3-O-glucoside chloride

Petunidin-3-O-glucoside chloride Chemical Structure

CAS No. : 6988-81-4

规格 价格 是否有货
5 mg ￥8800 询问价格 货期

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生物活性

Petunidin-3-O-glucoside chloride is a flavonoid isolated from Phaseolus vulgaris L. seed, has antioxidant activity[1]

分子量

514.86

Formula

C22H23ClO12
CAS 号

6988-81-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Clifford W Beninger, et al.Antioxidant activity of extracts, condensed tannin fractions, and pure flavonoids from Phaseolus vulgaris L. seed coat color genotypes. J Agric Food Chem

Delphinidin-3-O-galactoside chloride

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

Delphinidin-3-O-galactoside chloride;

Delphinidin-3-O-galactoside (chloride) 是从小麦粉中提取的花青素。Delphinidin-3-O-galactoside (chloride) 可用于抗氧化和抗菌的研究。

Delphinidin-3-O-galactoside chloride

Delphinidin-3-O-galactoside chloride Chemical Structure

CAS No. : 28500-00-7

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生物活性

Delphinidin-3-O-galactoside (chloride) is an anthocyanin that extracts from wheat flour. Delphinidin-3-O-galactoside (chloride) can be used for the research of antioxidant and antimicrobial[1].

分子量

500.84

Formula

C21H21ClO12
CAS 号

28500-00-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Seeram NP, et al. Characterization, quantification, and bioactivities of anthocyanins in Cornus species. J Agric Food Chem. 2002;50(9):2519-2523.

Malvidin-3-glucoside chloride(Synonyms: Malvidin-3-O-glucoside chloride; Oenin chloride)

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天然产物 糖类和糖苷 Saccharides and Glycosides

Malvidin-3-glucoside chloride;(Synonyms: Malvidin-3-O-glucoside chloride; Oenin chloride)

Malvidin-3-glucoside chloride (Malvidin-3-O-glucoside chloride)，是一种主要的葡萄酒花青素，通过调节大脑突触可塑性和外周炎症，有效地促进应激反应。

Malvidin-3-glucoside chloride(Synonyms: Malvidin-3-O-glucoside chloride; Oenin chloride)

Malvidin-3-glucoside chloride Chemical Structure

CAS No. : 7228-78-6

规格 价格 是否有货
1 mg ￥2600 询问价格 货期
5 mg ￥7000 询问价格 货期

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生物活性

Malvidin-3-glucoside chloride (Malvidin-3-O-glucoside chloride), a major wine anthocyanin, is effective in promoting resilience against stress by modulating brain synaptic plasticity and peripheral inflammation[1].

分子量

528.89

Formula

C23H25ClO12
CAS 号

7228-78-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Wang J, et al. Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice. Nat Commun. 2018;9(1):477. Published 2018 Feb 2.

Cyanidin 3-sambubioside chloride(Synonyms: Cyanidin-3-O-sambubioside chloride)

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

Cyanidin 3-sambubioside chloride;(Synonyms: Cyanidin-3-O-sambubioside chloride) 纯度: 98.40%

Cyanidin 3-sambubioside chloride (Cyanidin-3-O-sambubioside chloride)，一种主要的花色苷，一种天然着色剂，是一种有效的 NO 抑制剂。Cyanidin 3-sambubioside chloride 是 H274Y 突变抑制剂，可抑制流感神经氨酸酶 (neuraminidase) 活性，IC50 为 72 μM。Cyanidin 3-sambubioside chloride 抑制血管紧张素转换酶 (ACE) 的活性，并具有抗氧化，抗血管生成和抗病毒特性。

Cyanidin 3-sambubioside chloride(Synonyms: Cyanidin-3-O-sambubioside chloride)

Cyanidin 3-sambubioside chloride Chemical Structure

CAS No. : 33012-73-6

规格 价格 是否有货
5 mg ￥8800 询问价格 货期

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生物活性

Cyanidin 3-sambubioside chloride (Cyanidin-3-O-sambubioside chloride), a major anthocyanin, a natural colorant, and is a potent NO inhibitor. Cyanidin 3-sambubioside chloride is a H274Y mutation inhibitor, and inhibits influenza neuraminidase activity with an IC50 of 72 μM. Cyanidin 3-sambubioside chloride inhibits angiotensin-converting enzyme (ACE) activity and has antioxidant, anti-angiogenic and antiviral properties[1][2][3].

分子量

616.95

Formula

C26H29ClO15
CAS 号

33012-73-6
中文名称

氯化花青素-3-桑布双糖苷
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4deg;C, sealed storage, away from moisture and light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)
参考文献

  • [1]. Jung-Chu Cheng, et al. Detection of cyanidin in different-colored peanut testae and identification of peanut cyanidin 3-sambubioside. J Agric Food Chem. 2009 Oct 14;57(19):8805-11.

    [2]. S Kannan, et al. The inhibitory performance of flavonoid cyanidin-3-sambubiocide against H274Y mutation in H1N1 influenza virus. J Biomol Struct Dyn. 2018 Dec;36(16):4255-4269.

    [3]. Sang-Jin Lee, et al. Cyanidin-3-O-sambubioside from Acanthopanax sessiliflorus fruit inhibits metastasis by downregulating MMP-9 in breast cancer cells MDA-MB-231. Planta Med. 2013 Nov;79(17):1636-40.

Peonidin-3-O-galactoside chloride(Synonyms: 氯化芍药素-3-O-半乳糖苷；氯化芍药色素半乳糖苷)

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

Peonidin-3-O-galactoside chloride;(Synonyms: 氯化芍药素-3-O-半乳糖苷；氯化芍药色素半乳糖苷)

Peonidin-3-O-galactoside chloride 是一种具有抗氧化特性的花青素。

Peonidin-3-O-galactoside chloride(Synonyms: 氯化芍药素-3-O-半乳糖苷；氯化芍药色素半乳糖苷)

Peonidin-3-O-galactoside chloride Chemical Structure

CAS No. : 28148-89-2

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25 mg 询价

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生物活性

Peonidin-3-O-galactoside chloride is an anthocyanin with antioxidant properties[1].

分子量

498.86

Formula

C22H23ClO11
CAS 号

28148-89-2
中文名称

氯化芍药素-3-O-半乳糖苷；氯化芍药色素半乳糖苷
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Artemio Z Tulio Jr, et al. Phenolic composition, antioxidant properties, and endothelial cell function of red and white cranberry fruits. Food Chem. 2014 Aug 15;157:540-52.

Petunidin-3-O-galactoside chloride(Synonyms: 氯化矮牵牛素-3-O-半乳糖苷)

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

Petunidin-3-O-galactoside chloride;(Synonyms: 氯化矮牵牛素-3-O-半乳糖苷)

Petunidin-3-O-galactoside chloride 是一种具有抗氧化能力的类黄酮化合物。

Petunidin-3-O-galactoside chloride(Synonyms: 氯化矮牵牛素-3-O-半乳糖苷)

Petunidin-3-O-galactoside chloride Chemical Structure

CAS No. : 28500-02-9

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

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生物活性

Petunidin-3-O-galactoside chloride is a flavonoid compound with antioxidant capacity[1].

分子量

514.86

Formula

C22H23ClO12
CAS 号

28500-02-9
中文名称

氯化矮牵牛素-3-O-半乳糖苷
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Artemio Z Tulio Jr, et al. Berry fruits modulated endothelial cell migration and angiogenesis via phosphoinositide-3 kinase/protein kinase B pathway in vitro in endothelial cells. J Agric Food Chem. 2012 Jun 13;60(23):5803-12.

Pelargonidin 3-galactoside chloride

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

Pelargonidin 3-galactoside chloride;

Pelargonidin 3-galactoside chloride 是一种具有抗癌作用的主要花青素，可抑制 α-葡萄糖苷酶。

Pelargonidin 3-galactoside chloride

Pelargonidin 3-galactoside chloride Chemical Structure

CAS No. : 34425-22-4

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5 mg 询价
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25 mg 询价

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生物活性

Pelargonidin 3-galactoside chloride is a major anthocyanin with anticancer effects. Pelargonidin 3-galactoside chloride inhibits α-glucosidase[1].

体外研究
(In Vitro)

Pelargonidin 3-galactoside chloride has antiproliferative activity on human colon cancer cells (HT29)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

468.84

Formula

C21H21ClO10
CAS 号

34425-22-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Bojana Blagojević, et al. An in vitro and in silico evaluation of bioactive potential of cornelian cherry (Cornus mas L.) extracts rich in polyphenols and iridoids. Food Chem. 2021 Jan 15;335:127619.

Delphinidin 3-rutinoside chloride(Synonyms: Delphinidin 3-O-rutinoside chloride)

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

Delphinidin 3-rutinoside chloride;(Synonyms: Delphinidin 3-O-rutinoside chloride)

Delphinidin 3-rutinoside chloride (Delphinidin 3-O-rutinoside chloride) 是在欧洲越橘提取物中发现的一种活性花色苷。Delphinidin 3-rutinoside chloride 诱导 B 细胞慢性淋巴细胞性白血病 (B CLL) 的促凋亡作用。Delphinidin 3-rutinoside chloride 通过结合 ERβ 发挥植物雌激素活性，IC50 为 2.3 μM。

Delphinidin 3-rutinoside chloride(Synonyms: Delphinidin 3-O-rutinoside chloride)

Delphinidin 3-rutinoside chloride Chemical Structure

CAS No. : 15674-58-5

规格 是否有货
5 mg 询价
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25 mg 询价

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生物活性

Delphinidin 3-rutinoside chloride (Delphinidin 3-O-rutinoside chloride) is an active anthocyanin found in bilberry extract. Delphinidin 3-rutinoside chloride induces a pro-apoptotic effect in B cell chronic lymphocytic leukaemia (B CLL)[1]. Delphinidin 3-rutinoside chloride exerts phytoestrogen activity by binding to ERβ, with an IC50 of 2.3 μM[2].

分子量

646.98

Formula

C27H31ClO16
CAS 号

15674-58-5
中文名称

飞燕草素鼠李葡糖苷；氯化花翠素芦丁糖甙
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Mahmoud Alhosin, et al. Bilberry extract (Antho 50) selectively induces redox-sensitive caspase 3-related apoptosis in chronic lymphocytic leukemia cells by targeting the Bcl-2/Bad pathway. Sci Rep. 2015 Mar 11;5:8996.

Malvidin-3-O-arabinoside chloride

发表于由

天然产物 黄酮类 Flavonoids

Malvidin-3-O-arabinoside chloride 

Malvidin-3-O-arabinoside chloride 通过刺激 Ampk 介导的自噬 (autophagy)，改善氨基甲酸乙酯诱导的氧化损伤。

Malvidin-3-O-arabinoside chloride

Malvidin-3-O-arabinoside chloride Chemical Structure

CAS No. : 28500-04-1

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

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生物活性

Malvidin-3-O-arabinoside chloride ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy[1].

体外研究
(In Vitro)

Malvidin-3-O-arabinoside chloride (M3A chloride, 50-400 μM) pretreatment remarkably upregulates LAMP-1 expression, which indicates elevated lysosomal mass. M3A also successfully restores lysosomal acidity and subsequently strengthenes lysosomal functions. M3A stimulates phosphorylation of AMP-activated protein kinase (AMPK), a master regulator of autophagy[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Autophagy Assay[1]

Cell Line: Caco-2 cell line.
Concentration: 50, 100, 200 and 400 μM.
Incubation Time: 24 h (then treated with or without 10 μM chloroquine (CQ) for another 1 h).
Result: Notably inhibited excess ROS generation.
200 μM and 400 μM M3A pretreatment significantly enhanced 14% and 16% of GSH level.
Enhanced autophagy flux.
Significantly up-regulate the LC3-II/LC3-I ratio.

分子量

498.86

Formula

C22H23ClO11
CAS 号

28500-04-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Yuting Li, et al. Malvidin-3-O-arabinoside ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy. Food Funct. 2020 Dec 1;11(12):10317-10328.

Nicotinamide riboside chloride(Synonyms: 烟酰胺核糖氯酸盐)

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

Nicotinamide riboside chloride;(Synonyms: 烟酰胺核糖氯酸盐) 纯度: 99.53%

Nicotinamide riboside Chloride 是具有口服活性的 NAD+ 的前体，增加 NAD+ 水平并激活 SIRT1 和 SIRT3。Nicotinamide riboside Chloride 是维生素 B3 (烟酸) 的来源，可以增强氧化代谢并防止高脂肪饮食诱导的代谢异常。Nicotinamide riboside Chloride 可以减少阿尔茨海默氏病转基因小鼠模型中的认知退化。

Nicotinamide riboside chloride(Synonyms: 烟酰胺核糖氯酸盐)

Nicotinamide riboside chloride Chemical Structure

CAS No. : 23111-00-4

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
10;mM;*;1 mL in DMSO ￥550 In-stock
100 mg ￥500 In-stock
200 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

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生物活性

Nicotinamide riboside Chloride, an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3. Nicotinamide riboside Chloride is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities[1]. Nicotinamide riboside Chloride reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease[2].

IC50 Target[1]

SIRT1

;

SIRT3

;

Human Endogenous Metabolite

;

体外研究
(In Vitro)

Nicotinamide riboside Chloride (0.5 nM; 24 hours) reduces the acetylation status of Ndufa9 and SOD2[1].
Nicotinamide riboside Chloride increases intracellular and mitochondrial NAD+ content in C2C12, Hepa1.6, and HEK293 cells in a concentration-dependent manner at concentrations ranging from 1-1000 μM[1].
Nicotinamide riboside chloride boosts NAD to restore antiviral poly(ADP-ribose) polymerase (PARP) functions to support innate immunity for coronavirus (CoVs), a cause of COVID-19[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: HEK293T cells
Concentration: 0.5 nM
Incubation Time: 24 hours
Result: Reduced the acetylation status of Ndufa9 and SOD2.

体内研究
(In Vivo)

Chronic Nicotinamide riboside Chloride (p.o.; 400 mg/kg/day; for 16 weeks) supplementation increases plasma and intracellular NAD+ content in a tissue-specific manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 10-week-old C57Bl/6J mice[1]
Dosage: 400 mg/kg
Administration: PO; daily; for 16 weeks
Result: Increased plasma and intracellular NAD+ content in a tissue-specific manner.

Clinical Trial

分子量

290.70

Formula

C11H15ClN2O5
CAS 号

23111-00-4
中文名称

烟酰胺核糖氯酸盐
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4deg;C, sealed storage, away from moisture and light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)
溶解性数据
In Vitro:;

H2O : 125 mg/mL (430.00 mM; Need ultrasonic)

DMSO : 50 mg/mL (172.00 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.4400 mL 17.1999 mL 34.3997 mL
5 mM 0.6880 mL 3.4400 mL 6.8799 mL
10 mM 0.3440 mL 1.7200 mL 3.4400 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Cantó C, et al. The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protectsagainst high-fat diet-induced obesity. Cell Metab. 2012 Jun 6;15(6):838-47.

    [2]. Bing Gong, et al. Nicotinamide Riboside Restores Cognition Through an Upregulation of Proliferator-Activated Receptor-γ Coactivator 1α Regulated β-Secretase 1 Degradation and Mitochondrial Gene Expression in Alzheimer’s Mouse Models. Neurobiol Aging. 2013 Jun;34(6):1581-8.

    [3]. Collin D Heer, et al. Coronavirus and PARP Expression Dysregulate the NAD Metabolome: A Potentially Actionable Component of Innate Immunity. bioRxiv. 2020 Apr 30;2020.04.17.047480.