Pelargonidin 3-galactoside chloride

天然产物 糖类和糖苷 Saccharides and Glycosides

Pelargonidin 3-galactoside chloride;

Pelargonidin 3-galactoside chloride 是一种具有抗癌作用的主要花青素,可抑制 α-葡萄糖苷酶。

Pelargonidin 3-galactoside chloride

Pelargonidin 3-galactoside chloride Chemical Structure

CAS No. : 34425-22-4

规格 是否有货
5 mg 询价
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25 mg 询价

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生物活性

Pelargonidin 3-galactoside chloride is a major anthocyanin with anticancer effects. Pelargonidin 3-galactoside chloride inhibits α-glucosidase[1].

体外研究
(In Vitro)

Pelargonidin 3-galactoside chloride has antiproliferative activity on human colon cancer cells (HT29)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

468.84

Formula

C21H21ClO10

CAS 号

34425-22-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Bojana Blagojević, et al. An in vitro and in silico evaluation of bioactive potential of cornelian cherry (Cornus mas L.) extracts rich in polyphenols and iridoids. Food Chem. 2021 Jan 15;335:127619.

Delphinidin 3-rutinoside chloride(Synonyms: Delphinidin 3-O-rutinoside chloride)

天然产物 糖类和糖苷 Saccharides and Glycosides

Delphinidin 3-rutinoside chloride;(Synonyms: Delphinidin 3-O-rutinoside chloride)

Delphinidin 3-rutinoside chloride (Delphinidin 3-O-rutinoside chloride) 是在欧洲越橘提取物中发现的一种活性花色苷。Delphinidin 3-rutinoside chloride 诱导 B 细胞慢性淋巴细胞性白血病 (B CLL) 的促凋亡作用。Delphinidin 3-rutinoside chloride 通过结合 ERβ 发挥植物雌激素活性,IC50 为 2.3 μM。

Delphinidin 3-rutinoside chloride(Synonyms: Delphinidin 3-O-rutinoside chloride)

Delphinidin 3-rutinoside chloride Chemical Structure

CAS No. : 15674-58-5

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

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生物活性

Delphinidin 3-rutinoside chloride (Delphinidin 3-O-rutinoside chloride) is an active anthocyanin found in bilberry extract. Delphinidin 3-rutinoside chloride induces a pro-apoptotic effect in B cell chronic lymphocytic leukaemia (B CLL)[1]. Delphinidin 3-rutinoside chloride exerts phytoestrogen activity by binding to ERβ, with an IC50 of 2.3 μM[2].

分子量

646.98

Formula

C27H31ClO16

CAS 号

15674-58-5

中文名称

飞燕草素鼠李葡糖苷;氯化花翠素芦丁糖甙

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Mahmoud Alhosin, et al. Bilberry extract (Antho 50) selectively induces redox-sensitive caspase 3-related apoptosis in chronic lymphocytic leukemia cells by targeting the Bcl-2/Bad pathway. Sci Rep. 2015 Mar 11;5:8996.

Malvidin-3-O-arabinoside chloride

天然产物 黄酮类 Flavonoids

Malvidin-3-O-arabinoside chloride 

Malvidin-3-O-arabinoside chloride 通过刺激 Ampk 介导的自噬 (autophagy),改善氨基甲酸乙酯诱导的氧化损伤。

Malvidin-3-O-arabinoside chloride

Malvidin-3-O-arabinoside chloride Chemical Structure

CAS No. : 28500-04-1

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

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生物活性

Malvidin-3-O-arabinoside chloride ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy[1].

体外研究
(In Vitro)

Malvidin-3-O-arabinoside chloride (M3A chloride, 50-400 μM) pretreatment remarkably upregulates LAMP-1 expression, which indicates elevated lysosomal mass. M3A also successfully restores lysosomal acidity and subsequently strengthenes lysosomal functions. M3A stimulates phosphorylation of AMP-activated protein kinase (AMPK), a master regulator of autophagy[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Autophagy Assay[1]

Cell Line: Caco-2 cell line.
Concentration: 50, 100, 200 and 400 μM.
Incubation Time: 24 h (then treated with or without 10 μM chloroquine (CQ) for another 1 h).
Result: Notably inhibited excess ROS generation.
200 μM and 400 μM M3A pretreatment significantly enhanced 14% and 16% of GSH level.
Enhanced autophagy flux.
Significantly up-regulate the LC3-II/LC3-I ratio.

分子量

498.86

Formula

C22H23ClO11

CAS 号

28500-04-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Yuting Li, et al. Malvidin-3-O-arabinoside ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy. Food Funct. 2020 Dec 1;11(12):10317-10328.

Nicotinamide riboside chloride(Synonyms: 烟酰胺核糖氯酸盐)

天然产物 糖类和糖苷 Saccharides and Glycosides

Nicotinamide riboside chloride;(Synonyms: 烟酰胺核糖氯酸盐) 纯度: 99.53%

Nicotinamide riboside Chloride 是具有口服活性的 NAD+ 的前体,增加 NAD+ 水平并激活 SIRT1SIRT3。Nicotinamide riboside Chloride 是维生素 B3 (烟酸) 的来源,可以增强氧化代谢并防止高脂肪饮食诱导的代谢异常。Nicotinamide riboside Chloride 可以减少阿尔茨海默氏病转基因小鼠模型中的认知退化。

Nicotinamide riboside chloride(Synonyms: 烟酰胺核糖氯酸盐)

Nicotinamide riboside chloride Chemical Structure

CAS No. : 23111-00-4

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
10;mM;*;1 mL in DMSO ¥550 In-stock
100 mg ¥500 In-stock
200 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

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生物活性

Nicotinamide riboside Chloride, an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3. Nicotinamide riboside Chloride is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities[1]. Nicotinamide riboside Chloride reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease[2].

IC50 Target[1]

SIRT1

;

SIRT3

;

Human Endogenous Metabolite

;

体外研究
(In Vitro)

Nicotinamide riboside Chloride (0.5 nM; 24 hours) reduces the acetylation status of Ndufa9 and SOD2[1].
Nicotinamide riboside Chloride increases intracellular and mitochondrial NAD+ content in C2C12, Hepa1.6, and HEK293 cells in a concentration-dependent manner at concentrations ranging from 1-1000 μM[1].
Nicotinamide riboside chloride boosts NAD to restore antiviral poly(ADP-ribose) polymerase (PARP) functions to support innate immunity for coronavirus (CoVs), a cause of COVID-19[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: HEK293T cells
Concentration: 0.5 nM
Incubation Time: 24 hours
Result: Reduced the acetylation status of Ndufa9 and SOD2.

体内研究
(In Vivo)

Chronic Nicotinamide riboside Chloride (p.o.; 400 mg/kg/day; for 16 weeks) supplementation increases plasma and intracellular NAD+ content in a tissue-specific manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 10-week-old C57Bl/6J mice[1]
Dosage: 400 mg/kg
Administration: PO; daily; for 16 weeks
Result: Increased plasma and intracellular NAD+ content in a tissue-specific manner.

Clinical Trial

分子量

290.70

Formula

C11H15ClN2O5

CAS 号

23111-00-4

中文名称

烟酰胺核糖氯酸盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, sealed storage, away from moisture and light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)

溶解性数据
In Vitro:;

H2O : 125 mg/mL (430.00 mM; Need ultrasonic)

DMSO : 50 mg/mL (172.00 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.4400 mL 17.1999 mL 34.3997 mL
5 mM 0.6880 mL 3.4400 mL 6.8799 mL
10 mM 0.3440 mL 1.7200 mL 3.4400 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Cantó C, et al. The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protectsagainst high-fat diet-induced obesity. Cell Metab. 2012 Jun 6;15(6):838-47.

    [2]. Bing Gong, et al. Nicotinamide Riboside Restores Cognition Through an Upregulation of Proliferator-Activated Receptor-γ Coactivator 1α Regulated β-Secretase 1 Degradation and Mitochondrial Gene Expression in Alzheimer’s Mouse Models. Neurobiol Aging. 2013 Jun;34(6):1581-8.

    [3]. Collin D Heer, et al. Coronavirus and PARP Expression Dysregulate the NAD Metabolome: A Potentially Actionable Component of Innate Immunity. bioRxiv. 2020 Apr 30;2020.04.17.047480.

Kuromanin chloride(Synonyms: 矢车菊素-3-O-葡萄糖苷; Chrysontemin; Cyanidin 3-O-glucoside chloride)

天然产物 糖类和糖苷 Saccharides and Glycosides

Kuromanin chloride;(Synonyms: 矢车菊素-3-O-葡萄糖苷; Chrysontemin; Cyanidin 3-O-glucoside chloride) 纯度: 99.50%

矢车菊素-3-O-葡萄糖苷 (Kuromanin chloride) 来源于桑叶,具有提高血糖浓度、维持脂质代谢平衡以降低肥胖的作用。

Kuromanin chloride(Synonyms: 矢车菊素-3-O-葡萄糖苷; Chrysontemin;  Cyanidin 3-O-glucoside chloride)

Kuromanin chloride Chemical Structure

CAS No. : 7084-24-4

规格 价格 是否有货 数量
10;mM;*;1 mL in DMSO ¥1152 In-stock
2 mg ¥550 In-stock
5 mg ¥1080 In-stock
10 mg ¥1580 In-stock
25 mg ¥3160 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

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生物活性

Kuromanin (chloride), extracted from mulberry leaves, has been shown to improve blood glucose concentrations and lipid homeostasis and to reduce obesity.

分子量

484.84

Formula

C21H21ClO11

CAS 号

7084-24-4

中文名称

矢车菊素-3-O-葡萄糖苷

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, sealed storage, away from moisture

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro:;

DMSO : 25 mg/mL (51.56 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.0625 mL 10.3127 mL 20.6254 mL
5 mM 0.4125 mL 2.0625 mL 4.1251 mL
10 mM 0.2063 mL 1.0313 mL 2.0625 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂:;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.08 mg/mL (4.29 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (4.29 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂:;10% DMSO ;; 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (4.29 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (4.29 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中,混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中,再用生理盐水定容至 10 mL,完全溶解,澄清透明
*以上所有助溶剂都可在 MCE 网站选购。
参考文献
  • [1]. Ha -Na Na, et al. Reduction of adenovirus 36-induced obesity andin?ammation by mulberry extract. Microbiol Immunol 2014; 58: 303–306

INT(Synonyms: Iodonitrotetrazolium chloride; p-Iodonitrotetrazolium Violet)

生化分析试剂 Biochemical Assay Reagents
INT;(Synonyms: Iodonitrotetrazolium chloride; p-Iodonitrotetrazolium Violet) 纯度: 98.23%

INT(Iodonitrotetrazolium chloride)可用于脱氢酶比色法测定电子受体。

INT(Synonyms: Iodonitrotetrazolium chloride;  p-Iodonitrotetrazolium Violet)

INT Chemical Structure

CAS No. : 146-68-9

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
10;mM;*;1 mL in DMSO ¥550 In-stock
500 mg ¥500 In-stock
1 g ¥850 In-stock
5 g ¥3300 In-stock
10 g ; 询价 ;
50 g ; 询价 ;

* Please select Quantity before adding items.

INT 相关产品

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  • Bioactive Compound Library Plus

生物活性

INT(Iodonitrotetrazolium chloride) is used in various dehydrogenase colorimetric analysis of the electron acceptor.

分子量

505.70

Formula

C19H13ClIN5O2

CAS 号

146-68-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, sealed storage, away from moisture

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro:;

DMSO : 83.33 mg/mL (164.78 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.9775 mL 9.8873 mL 19.7746 mL
5 mM 0.3955 mL 1.9775 mL 3.9549 mL
10 mM 0.1977 mL 0.9887 mL 1.9775 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂:;10% DMSO ;; 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (4.11 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (4.11 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中,混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中,再用生理盐水定容至 10 mL,完全溶解,澄清透明
*以上所有助溶剂都可在 MCE 网站选购。

Ammonium chloride

生化分析试剂 Biochemical Assay Reagents
Ammonium chloride;

Ammonium chloride 作为调节 pH 值的异极性化合物,可引起细胞内碱化和代谢性酸中毒,从而影响酶的活性,影响生物系统的进程。Ammonium chloride 作为一种自噬 (autophagy) 抑制剂。

Ammonium chloride

Ammonium chloride Chemical Structure

CAS No. : 12125-02-9

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
250 mg ¥350 In-stock
500 mg ; 询价 ;
1 g ; 询价 ;

* Please select Quantity before adding items.

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生物活性

Ammonium chloride, as a heteropolar compound with pH value regulation, can cause intracellular alkalization and metabolic acidosis thus effecting enzymatic activity and influencing the process of biological system. Ammonium chloride is an autophagy inhibitor[1][2].

体外研究
(In Vitro)

Ammonium chloride (NH4Cl), a lysosomotropic agent that raises intralysosomal pH, reduces the yield of reovirus during infection of mouse L cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Ammonium chloride (0.28 M in drinking water) promotes the survival of myocardial cells in vivo by decreasing contractile dysfunction, cardiac hypertrophy, inflammation, apoptosis and autophagy[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 8-9-week-old C57B/L6 mice[1]
Dosage: 0.28 M in drinking water (5 mg/kg doxorubicin once a week for 2 weeks)
Administration: 0.28 M in drinking water (5 mg/kg doxorubicin once a week for 2 weeks)
Result: Effectively improved doxorubicin (DOX)-induced cardiomyocyte apoptosis and cardiac dysfunction in mice.

分子量

53.49

Formula

ClH4N

CAS 号

12125-02-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : 100 mg/mL (1869.51 mM; Need ultrasonic)

DMSO : 50 mg/mL (934.75 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 18.6951 mL 93.4754 mL 186.9508 mL
5 mM 3.7390 mL 18.6951 mL 37.3902 mL
10 mM 1.8695 mL 9.3475 mL 18.6951 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂:;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.5 mg/mL (46.74 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (46.74 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂:;10% DMSO ;; 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (46.74 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (46.74 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中,混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中,再用生理盐水定容至 10 mL,完全溶解,澄清透明
  • 3.

    请依序添加每种溶剂:;10% DMSO ;; 90% corn oil

    Solubility: ≥ 2.5 mg/mL (46.74 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (46.74 mM,饱和度未知) 的澄清溶液,此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中,混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。
参考文献
  • [1]. Huang X, et al. NH4Cl treatment prevents doxorubicin-induced myocardial dysfunction in vivo. Life Sci. 2019;227:94-100.

    [2]. Canning WM, Fields BN. Ammonium chloride prevents lytic growth of reovirus and helps to establish persistent infection in mouse L cells. Science. 1983;219(4587):987-988.

Peonidin chloride(Synonyms: YGM-6 chloride)

天然产物 黄酮类 Flavonoids

Peonidin chloride (Synonyms: YGM-6 chloride)

Peonidin chloride 是一种 O-甲基化的花青素,作为一种主要的植物色素,赋予牡丹等花以紫红色的色调,因此得名,同时也赋予浆果和蔬菜以紫红色。Peonidin chloride 在体外对癌细胞具有化学预防和抗炎活性,阻断 JB6 P+ 小鼠表皮细胞 COX-2 的表达和转化。

Peonidin chloride(Synonyms: YGM-6 chloride)

Peonidin chloride Chemical Structure

CAS No. : 134-01-0

规格 价格 是否有货
5 mg ¥4200 询问价格 & 货期

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生物活性

Peonidin chloride is an O-methylated anthocyanidin that functions as a primary plant pigment, endowing purplish-red hues to flowers such as the peony, from which it takes its name, as well as berries and vegetables. Peonidin chloride exhibits chemopreventive, as well as anti-inflammatory activities on cancer cells in vitro, blocking COX-2 expression and transformation in JB6 P+ mouse epidermal cells.

IC50 & Target

COX-2

 

分子量

336.72

Formula

C16H13ClO6

CAS 号

134-01-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Potassium chloride,AR,99.5%

生化分析试剂 Biochemical Assay Reagents
Potassium chloride,AR,99.5%; 纯度: ge;99.0%

Potassium chloride,AR,99.5% 被广泛用作钾补充剂。Potassium chloride,AR,99.5% 是一种容易获得的钾肥。

Potassium chloride,AR,99.5%

Potassium chloride,AR,99.5% Chemical Structure

CAS No. : 7447-40-7

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
500 g ¥350 In-stock
1 mg ; 询价 ;
5 mg ; 询价 ;

* Please select Quantity before adding items.

Potassium chloride,AR,99.5% 相关产品

bull;相关化合物库:

  • Drug Repurposing Compound Library Plus
  • FDA-Approved Drug Library Plus
  • Bioactive Compound Library Plus
  • FDA-Approved Drug Library
  • Fragment Library
  • Drug Repurposing Compound Library
  • NMPA-Approved Drug Library
  • Orally Active Compound Library
  • FDA Approved amp; Pharmacopeial Drug Library
  • Food Additive Library
  • Inactive Ingredient Library
  • Childrenrsquo;s Drug Library

生物活性

Potassium chloride,AR,99.5% is extensively used as a potassium supplement. Potassium chloride,AR,99.5% is a readily available potassium fertilizer[1].

分子量

74.55

Formula

ClK

CAS 号

7447-40-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
参考文献
  • [1]. Fujimura S, et al. The inhibitory effects of potassium chloride versus potassium silicate application on (137)Cs uptake by rice. J Environ Radioact. 2016;153:188-194.

    [2]. Saxena K. Clinical features and management of poisoning due to potassium chloride. Med Toxicol Adverse Drug Exp. 1989;4(6):429-443.

Rhodamine-N3 chloride

Rhodamine-N3 chloride; 纯度: 97.06%

Rhodamine-N3 chloride 是一种叠氮化物-罗丹明荧光染料,可用于标记含有炔基的生物分子。

Rhodamine-N3 chlorideamp;;

Rhodamine-N3 chloride Chemical Structure

CAS No. : 2363751-90-8

规格 价格 是否有货 数量
5 mg ¥3500 In-stock
10 mg ¥5800 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

Rhodamine-N3 chloride 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus

生物活性

Rhodamine-N3 chloride is an azide-rhodamine fluorescent dye that can be used to label biomolecules containing alkyne groups[1][2].

体外研究
(In Vitro)

The cell lysates or cells are treated with probes (0.001-10 μM, 1 hr), and then reacted with an Rhodamine-N3 (N3-Rh) reporter tag under copper-catalyzed azide-alkyne cycloaddition (CuACC or click chemistry) conditions and probe-labeled proteins visualized by SDS-PAGE and in-gel fluorescence scanning[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

847.44

Formula

C44H59ClN8O7

CAS 号

2363751-90-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, sealed storage, away from moisture

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro:;

DMSO : 3.33 mg/mL (3.93 mM; ultrasonic and warming and heat to 60°C)

H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.1800 mL 5.9001 mL 11.8002 mL
5 mM
10 mM

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Shijiao Cai, et al. Glycyrrhizic Acid-Induced Differentiation Repressed Stemness in Hepatocellular Carcinoma by Targeting c-Jun N-Terminal Kinase 1. Front Oncol. 2020 Jan 9;9:1431.

    [2]. Bryan R Lanning, et al. A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors. Nat Chem Biol. 2014 Sep;10(9):760-767.