Parathyroid Hormone (PTH)(44-68)(Human) 品牌：Anygen

生物活性	Egg Laying Hormone, aplysia is a neuropeptide synthesized by the bag cell neurons, which contains 36 amino acids and can stimulate egglaying and ovulation in Aplysia via electrical discharge triggering of neurons. Egg-laying hormone of Aplysia induces a voltage-dependent slow inward current carried by Na’ in an identified motoneuron^[1]^[2].
分子量	4384.20
Formula	C₁₉₀H₃₂₉N₅₉O₅₇S
CAS 号	117680-39-4
Sequence	Ile-Ser-Ile-Asn-Gln-Asp-Leu-Lys-Ala-Ile-Thr-Asp-Met-Leu-Leu-Thr-Glu-Gln-Ile-Arg-Glu-Arg-Gln-Arg-Tyr-Leu-Ala-Asp-Leu-Arg-Gln-Arg-Leu-Leu-Glu-Lys-NH2
Sequence Shortening	ISINQDLKAITDMLLTEQIRERQRYLADLRQRLLEK-NH2
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Kirk MD, et al. Egg-laying hormone of Aplysia induces a voltage-dependent slow inward current carried by Na+ in an identified motoneuron. Proc Natl Acad Sci U S A. 1986 May;83(9):3017-21. [2]. Nuurai P, et al. Stimulatory Effects of Egg-Laying Hormone and Gonadotropin-Releasing Hormone on Reproduction of the Tropical Abalone, Haliotis asinina Linnaeus. Journal of Shellfish Research, 2010, 29(3):627-635.

Parathyroid Hormone (1-34), bovine

发表于2024年7月15日由Whatman官网

Parathyroid Hormone (1-34), bovine;

Parathyroid Hormone (1-34), bovine 是一种有效的甲状旁腺激素 (PTH) 受体激动剂。Parathyroid Hormone (1-34), bovine 增加钙和无机磷酸盐的水平。Parathyroid Hormone (1-34), bovine 可用于研究骨质疏松症。

Parathyroid Hormone (1-34), bovine Chemical Structure

CAS No. : 12583-68-5

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

* Please select Quantity before adding items.

生物活性

Parathyroid Hormone (1-34), bovine is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis^[1].

体外研究
(In Vitro)

Parathyroid Hormone (1-34), bovine (0.1-100 ng/mL; 2-20 days) are added to the medium, it inhibits osteoblast proliferation in a dose-dependent manner. In another group, bPTH are added to the culture medium from day 1 to day 10, but not from days 11 to 20, a rebound of proliferation is observed in the PTH Day 1–10 group after bPTH withdrawal^[1].
Parathyroid Hormone (1-34), bovine (0.1-100 ng/mL; 2-20 days) induces diverse effects on the calcium and phosphorus content of culture medium. The calcium and phosphorus content of culture medium in the PTH-C 100 ng/mL group are higher than in teh control group^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay^[1]

Cell Line:	MC3T3-E1 cells
Concentration:	0.1-100 ng/mL
Incubation Time:	2-20 days
Result:	Resulted a decrease of osteoblast proliferationin concentration-dependent manner. Resulted in a rebound of proliferation when PTH withdrawal.

体内研究
(In Vivo)

Parathyroid Hormone (1-34)(subcutaneous injection; 80 μg/kg; 5 days) increases serum osteocalcin concentrations without changing serum inorganic phosphate or calcium concentrations in either group of old animals. Serum 1,25-dihydroxyvitamin D concentrations are significantly higher in the PTH-treated senile female rats than the sex-matchedvehicle-treated controls^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

4108.77

Formula

C₁₈₃H₂₈₈N₅₄O₅₀S₂

CAS 号

12583-68-5

Sequence Shortening

AVSEIQFMHNGKHLSSMERVEWLRKKLQDVHNF

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. B H Mitlak, et al. Intermittent administration of bovine PTH-(1-34) increases serum 1,25-dihydroxyvitamin D concentrations and spinal bone density in senile (23 month) rats. J Bone Miner Res. 1992 May;7(5):479-84.

[2]. M Takigawa, et al. Studies on chondrocytes from mandibular condylar cartilage, nasal septal cartilage, and spheno-occipital synchondrosis in culture. I. Morphology, growth, glycosaminoglycan synthesis, and responsiveness to bovine parathyroid hormone (1-34). J Dent Res. 1984 Jan;63(1):19-22.

Adipokinetic Hormone (AKH) (24-32), locust TFA

发表于2024年7月11日由Whatman官网

Adipokinetic Hormone (AKH) (24-32), locust TFA;

Adipokinetic Hormone (AKH) (24-32), locust (TFA)，可从从蝗虫心脏分离得到，是调节飞行中脂质利用的神经激素。

Adipokinetic Hormone (AKH) (24-32), locust TFA Chemical Structure

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

* Please select Quantity before adding items.

生物活性

Adipokinetic Hormone (AKH) (24-32), locust (TFA), isolated from locust corpora cardiaca, is a neurohormone that regulates lipid utilisation during flight^[1].

体外研究
(In Vitro)

Adipokinetic hormone (AKH) peptides in insects serve the endocrine control of energy supply. They also produce, however, neuronal, vegetative, and motor effects, suggesting that AKHs orchestrate adaptive behavior by multiple actions^[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1273.29

Formula

C₅₆H₇₅N₁₄F₃O₁₇

Sequence Shortening

{Pyr}-LNFTPNWGT-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility

In Vitro:;

H₂O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

;	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3.;;Recommended solution:

Overall charge of peptide	Details
Negative (lt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, add NH₄OH (lt;50 μL). 3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

参考文献

[1]. J V Stone, et al. Structure of Locust Adipokinetic Hormone, a Neurohormone That Regulates Lipid Utilisation During Flight. Nature. 1976 Sep 16;263(5574):207-11.

[2]. Dieter Wicher, et al. Differential Receptor Activation by Cockroach Adipokinetic Hormones Produces Differential Effects on Ion Currents, Neuronal Activity, and Locomotion. J Neurophysiol. 2006 Apr;95(4):2314-25.

Parathyroid Hormone (1-34), bovine TFA

发表于2024年7月6日由Whatman官网

Parathyroid Hormone (1-34), bovine TFA;

Parathyroid Hormone (1-34), bovine TFA 是一种有效的甲状旁腺激素 (PTH) 受体激动剂。Parathyroid Hormone (1-34), bovine 增加钙和无机磷酸盐的水平。Parathyroid Hormone (1-34), bovine 可用于研究骨质疏松症。

Parathyroid Hormone (1-34), bovine TFA Chemical Structure

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

* Please select Quantity before adding items.

生物活性	Parathyroid Hormone (1-34), bovine TFA is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis^[1].
体外研究 (In Vitro)	Parathyroid Hormone (1-34), bovine (0.1-100 ng/mL; 2-20 days) are added to the medium, it inhibits osteoblast proliferation in a dose-dependent manner. In another group, bPTH are added to the culture medium from day 1 to day 10, but not from days 11 to 20, a rebound of proliferation is observed in the PTH Day 1–10 group after bPTH withdrawal^[1]. Parathyroid Hormone (1-34), bovine (0.1-100 ng/mL; 2-20 days) induces diverse effects on the calcium and phosphorus content of culture medium. The calcium and phosphorus content of culture medium in the PTH-C 100 ng/mL group are higher than in the control group^[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究 (In Vivo)	Parathyroid Hormone (1-34)(subcutaneous injection; 80 μg/kg; 5 days) increases serum osteocalcin concentrations without changing serum inorganic phosphate or calcium concentrations in either group of old animals. Serum 1,25-dihydroxyvitamin D concentrations are significantly higher in the PTH-treated senile female rats than the sex-matchedvehicle-treated controls^[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	4222.79
Formula	C₁₈₅H₂₈₉F₃N₅₄O₅₂S₂
Sequence Shortening	AVSEIQFMHNGKHLSSMERVEWLRKKLQDVHNF
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. B H Mitlak, et al. Intermittent administration of bovine PTH-(1-34) increases serum 1,25-dihydroxyvitamin D concentrations and spinal bone density in senile (23 month) rats. J Bone Miner Res. 1992 May;7(5):479-84. [2]. M Takigawa, et al. Studies on chondrocytes from mandibular condylar cartilage, nasal septal cartilage, and spheno-occipital synchondrosis in culture. I. Morphology, growth, glycosaminoglycan synthesis, and responsiveness to bovine parathyroid hormone (1-34). J Dent Res. 1984 Jan;63(1):19-22.

Melanin Concentrating Hormone (Rat) 黑色素聚集激素品牌：FUJIFILM Wako

发表于2024年6月26日由Whatman官网

Melanin Concentrating Hormone (Rat)

黑色素聚集激素

品牌：FUJIFILM Wako
CAS No.：128315-56-0
储存条件：-20℃
纯度：–

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
138-14641	for Cellbiology	1 mg	–		–	–

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Parathyroid hormone (1-34) (rat)

发表于2024年5月3日由Whatman官网

Parathyroid hormone (1-34) (rat); 纯度: 95.53%

Parathyroid hormone (1-34) (rat) 是甲状旁腺激素，可改善皮质和松质骨结构。

Parathyroid hormone (1-34) (rat) Chemical Structure

CAS No. : 98614-76-7

规格	价格	是否有货	数量
1 mg	￥3200	In-stock
5 mg	￥9000	In-stock
10 mg	;	询价	;
50 mg	;	询价	;

* Please select Quantity before adding items.

生物活性

Parathyroid hormone (1-34) (rat) improves both cortical and cancellous bone structure^[1].

体内研究
(In Vivo)

PTH (80 μg/kg per day (hPTH), s.c., 4 weeks ) induces a ~35% recovery of this loss and a ~40% reversal of the associated decreases in trabecular number (Tb.N) and connectivity. PTH also causes a shift from single to double calcein-labeled trabecular surfaces, a significant enhancement in the mineralizing perimeter and a respective 2- and 3-fold stimulation of the mineral appositional rate (MAR) and bone formation rate (BFR)^[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Sixty-three 11-week-old virgin female Swiss-Webster mice^[2].
Dosage:	80 μg/kg per day (hPTH).
Administration:	S.C., 4 weeks (5 days a week).
Result:	OVX osteoporotic mice respond to PTH by increased osteoblast activity and the consequent restoration of trabecular network.

分子量

4057.71

Formula

C₁₈₀H₂₉₁N₅₅O₄₈S₂

CAS 号

98614-76-7

Sequence Shortening

AVSEIQLMHNLGKHLASVERMQWLRKKLQDVHNF

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-80deg;C	2 years
	-20deg;C	1 year
In solvent	-80deg;C	6 months
	-20deg;C	1 month

Solvent Solubility

In Vitro:;

H₂O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

;	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3.;;Recommended solution:

Overall charge of peptide	Details
Negative (lt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, add NH₄OH (lt;50 μL). 3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

Luteinizing hormone (human)(Synonyms: 黄体生成素 (人))

发表于2024年4月9日由Whatman官网

Luteinizing hormone (human);(Synonyms: 黄体生成素 (人))

Luteinizing hormone (human) 是垂体 (LH) 产生的一种异二聚体糖蛋白激素，在人类生殖中起关键作用。

Luteinizing hormone (human)amp;;(Synonyms: 黄体生成素 (人))

Luteinizing hormone (human) Chemical Structure

CAS No. : 39341-83-8

规格	价格	是否有货
10 μg	￥7350	询问价格货期

* Please select Quantity before adding items.

生物活性

Luteinizing hormone (human), a heterodimeric glycoprotein hormone produced by the pituitary gland (LH), plays key roles in human reproduction^[1].

IC₅₀ Target

LHR^[1]

体外研究
(In Vitro)

Luteinizing hormone (human) binds to luteinizing hormone receptor (LHR) in human and non-human species which are mainly expressed in the ovary and testis^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CAS 号

39341-83-8

中文名称

黄体生成素 (人)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-80deg;C	2 years
	-20deg;C	1 year
In solvent	-80deg;C	6 months
	-20deg;C	1 month

Solvent Solubility

In Vitro:;

H₂O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

;	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3.;;Recommended solution:

Overall charge of peptide	Details
Negative (lt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, add NH₄OH (lt;50 μL). 3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

参考文献

[1]. Laura Riccetti, et al. Human Luteinizing Hormone and Chorionic Gonadotropin Display Biased Agonism at the LH and LH/CG Receptors. Sci Rep. 2017 Apr 19;7(1):940.

Adipokinetic Hormone G (AKH-G) (Gryllus bimaculatus) 品牌：Anygen

发表于2024年3月31日由Whatman官网

Adipokinetic Hormone G (AKH-G) (Gryllus bimaculatus)

品牌：Anygen
CAS No.：
储存条件：-20℃
纯度：–

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
309-91751	–	0.5 mg	–	咨询	–	–

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标签归档：hormone

Parathyroid Hormone (PTH)(44-68)(Human) 品牌：Anygen

Parathyroid Hormone (PTH)(44-68)(Human)

Parathyroid Hormone (Human, 1-34) 品牌：Peptide

Parathyroid Hormone (Human, 1-34)

Egg Laying Hormone, aplysia

Parathyroid Hormone (1-34), bovine

Adipokinetic Hormone (AKH) (24-32), locust TFA

Parathyroid Hormone (1-34), bovine TFA

Melanin Concentrating Hormone (Rat) 黑色素聚集激素品牌：FUJIFILM Wako

Melanin Concentrating Hormone (Rat)

黑色素聚集激素

Parathyroid hormone (1-34) (rat)

Luteinizing hormone (human)(Synonyms: 黄体生成素 (人))

Adipokinetic Hormone G (AKH-G) (Gryllus bimaculatus) 品牌：Anygen

Adipokinetic Hormone G (AKH-G) (Gryllus bimaculatus)

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