Anti-β3-Adrenergic Receptor, Rabbit-Poly 品牌:Transgenic


Anti-β3-Adrenergic Receptor, Rabbit-Poly

品牌:Transgenic
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储存条件:-20℃
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KG115

100 ug 咨询


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Anti Macrophage Scavenger Receptor 1 (MSR1/CD204) mAb (Clone SRA-E5) 品牌:Cosmo Bio


Anti Macrophage Scavenger Receptor 1 (MSR1/CD204) mAb (Clone SRA-E5)

品牌:Cosmo Bio
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CAC-KMU-MA01

50 µg 咨询


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Interleukin-1 Receptor Antagonist(IL-1Ra), Human, recombinant 白介素-1受体拮抗剂(IL-1Ra),人,重组体 品牌:FUJIFILM Wako


Interleukin-1 Receptor Antagonist(IL-1Ra), Human, recombinant

白介素-1受体拮抗剂(IL-1Ra),人,重组体

品牌:FUJIFILM Wako
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储存条件:-20℃
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(生产商编号)

等级 规格 运输包装 零售价(RMB) 库存情况 参考值

093-05991

for Cellbiology 100ug 4,940.00


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TWEAK Receptor soluble, Human, recombinant TWEAK受体溶液,人,重组 品牌:FUJIFILM Wako


TWEAK Receptor soluble, Human, recombinant

TWEAK受体溶液,人,重组

品牌:FUJIFILM Wako
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204-18951

for Cellbiology 25ug 4,760.00


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Interleukin-6 Receptor α soluble(sIL-6Rα), Human, recombinant 品牌:FUJIFILM Wako


Interleukin-6 Receptor α soluble(sIL-6Rα), Human, recombinant

品牌:FUJIFILM Wako
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储存条件:-20℃
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(生产商编号)

等级 规格 运输包装 零售价(RMB) 库存情况 参考值

090-06001

for Cellbiology 20 ug

Interleukin-6 Receptor α soluble(sIL-6Rα), Human, recombinant                                                                品牌:FUJIFILM Wako

替代品:092-07301


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A-71915 TFA

A-71915 TFA;

A-71915 (TFA) 是一种选择性的心房利钠肽受体 (ANP receptor) 抑制剂,可诱导 RINm5F 胰腺 β 细胞的凋亡,降低胰岛素的分泌。

A-71915 TFAamp;;

A-71915 TFA Chemical Structure

规格 是否有货
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生物活性

A-71915 (TFA) is a selective inhibitor of ANP receptor (atrial natriuretic peptide-receptor), induces apoptosis and decreases insulin secretion in RINm5F pancreatic β-cells[1].

分子量

1727.98

Formula

C71H117F3N26O17S2

Sequence Shortening

RC-{Cyclohexyl-Ala}-GGRIDRI-{d-Tic}-RC (Disulfide bridge: Cys2-Cys13)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Wong JC, et al. Pancreatic-β-cell survival and proliferation are promoted by protein kinase G type Iα and downstream regulation of AKT/FOXO1. Diab Vasc Dis Res. 2017 Sep;14(5):434-449.

Interleukin-4 Receptor α soluble(sIL-4Rα), Human, recombinant 品牌:FUJIFILM Wako


Interleukin-4 Receptor α soluble(sIL-4Rα), Human, recombinant

品牌:FUJIFILM Wako
CAS No.:
储存条件:-20℃
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产品编号

(生产商编号)

等级 规格 运输包装 零售价(RMB) 库存情况 参考值

099-06071

for Cellbiology 15 ug

Interleukin-4 Receptor α soluble(sIL-4Rα), Human, recombinant                                                                品牌:FUJIFILM Wako


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Galanin Receptor Ligand M35 TFA

Galanin Receptor Ligand M35 TFA;

Galanin Receptor Ligand M35 TFA 是一种高亲和力的甘丙肽受体 (galanin receptor) 配体 (Kd=0.1 nM),也是 galanin receptor 拮抗剂。Galanin Receptor Ligand M35 TFA 对人甘丙肽受体 1 型 和 人甘丙肽受体 2 型 的 Ki 值分别为 0.11 nM、2.0 nM。

Galanin Receptor Ligand M35 TFAamp;;

Galanin Receptor Ligand M35 TFA Chemical Structure

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Galanin Receptor Ligand M35 TFA 的其他形式现货产品:

Galanin Receptor Ligand M35

生物活性

Galanin Receptor Ligand M35 TFA is a high-affinity ligand and antagonist of galanin receptor (Kd=0.1 nM). Galanin Receptor Ligand M35 TFA exerts a Ki values of 0.11 and 2.0 nM for human galanin receptor type 1 and 2, respectively[1][2].

体外研究
(In Vitro)

Galanin Receptor Ligand M35 TFA has a dual effect on the galanin mediated inhibition of Forskolin stimulated cyclic AMP production in Rin m 5F cells. Co-applied with galanin (10 nM), Galanin Receptor Ligand M35 TFA at low concentrations (1 nM) is able to reverse the inhibitory effect of galanin. But when present at higher concentrations (15 and 30 nM), Galanin Receptor Ligand M35 TFA acts as a galanin receptor agonist, inhibiting the forskolin stimulated production of cAMP[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Galanin Receptor Ligand M35 TFA (6 nM/10 μL; i.c.v.) improves the ability of the male Sprague-Dnwley rats to acquire the swim maze task[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

2347.62

Formula

C109H154N27F3O28

Sequence

Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-NH2

Sequence Shortening

GWTLNSAGYLLGPPPGFSPFR-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Kask K, et al. Binding and agonist/antagonist actions of M35, galanin(1-13)-bradykinin(2-9)amide chimeric peptide, in Rin m 5F insulinoma cells. Regul Pept. 1995 Nov 10;59(3):341-8.

    [2]. Webling KE, et al. Galanin receptors and ligands. Front Endocrinol (Lausanne). 2012 Dec 7;3:146.

    [3]. Ogren SO, et al. Evidence for a role of the neuropeptide galanin in spatial learning. Neuroscience. 1992 Nov;51(1):1-5.

Thrombin Receptor Activator for Peptide 5 (TRAP-5)

Thrombin Receptor Activator for Peptide 5 (TRAP-5);

Thrombin Receptor Activator for Peptide 5 (TRAP-5) 又叫作凝血因子 II 受体 (1-5) 或蛋白酶激活受体 1 (1-5) (Proteinase Activated Receptor 1 (1-5)),可用于冠心病的研究。

Thrombin Receptor Activator for Peptide 5 (TRAP-5)amp;;

Thrombin Receptor Activator for Peptide 5 (TRAP-5) Chemical Structure

CAS No. : 141685-53-2

规格 价格 是否有货
1 mg ¥800 询问价格 货期
5 mg ¥1800 询问价格 货期
10 mg ¥2800 询问价格 货期

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生物活性

Thrombin Receptor Activator for Peptide 5 (TRAP-5) is also called Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), used in the research of coronary heart disease (CHD).

IC50 Target

Protease-Activated Receptor

分子量

634.77

Formula

C30H50N8O7

CAS 号

141685-53-2

Sequence Shortening

SFLLR

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Gigante B, et al. Retrospective analysis of coagulation factor II receptor (F2R) sequence variation and coronary heart disease in hypertensive patients. Arterioscler Thromb Vasc Biol. 2007 May;27(5):1213-9.

Neuropeptide Y Y1 receptor antagonist 1

Neuropeptide Y Y1 receptor antagonist 1;

Neuropeptide Y Y1 receptor antagonist 1 (化合物 39),一种荧光探针,是神经肽 Y Y1 受体 (Y1R) 的拮抗剂,Ki 值为 0.19 nM。

Neuropeptide Y Y1 receptor antagonist 1amp;;

Neuropeptide Y Y1 receptor antagonist 1 Chemical Structure

规格 是否有货
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生物活性

Neuropeptide Y Y1 receptor antagonist 1 (compound 39), a fluorescent probe, is a potent antagonist of neuropeptide Y Y1 receptor (Y1R), with a Ki of 0.19 nM[1].

IC50 Target[1]

NPY Y1 receptor

0.19 nM (Ki)

分子量

1115.28

Formula

C62H70N10O10

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Müller C, et, al. Structure-Based Design of High-Affinity Fluorescent Probes for the Neuropeptide Y Y 1 Receptor. J Med Chem. 2022 Mar 24;65(6):4832-4853.