分类目录归档：黄酮类

天然产物黄酮类

5-Methyl-7-methoxyisoflavone

发表于由

天然产物 黄酮类 Flavonoids

5-Methyl-7-methoxyisoflavone  纯度: 99.74%

5-Methyl-7-methoxyisoflavone 是一种非甾体合成代谢异黄酮。5-Methyl-7-methoxyisoflavone 可增加肌肉质量和耐力。

5-Methyl-7-methoxyisoflavone

5-Methyl-7-methoxyisoflavone Chemical Structure

CAS No. : 82517-12-2

规格 价格 是否有货 数量
5 mg ￥500 In-stock
10 mg ￥800 In-stock
20 mg ￥1400 In-stock
50 mg   询价  
100 mg   询价  

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5-Methyl-7-methoxyisoflavone 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Natural Product Library
  • Traditional Chinese Medicine Monomer Library
  • Flavonoids Library

生物活性

5-Methyl-7-methoxyisoflavone is a sensational, non-steroidal anabolic isoflavone. 5-Methyl-7-methoxyisoflavone shows potency increasing muscle mass and endurance[1].

分子量

266.29

Formula

C17H14O3
CAS 号

82517-12-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

DMSO : 125 mg/mL (469.41 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.7553 mL 18.7765 mL 37.5530 mL
5 mM 0.7511 mL 3.7553 mL 7.5106 mL
10 mM 0.3755 mL 1.8777 mL 3.7553 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂： 10% DMSO    90% corn oil

    Solubility: ≥ 6.25 mg/mL (23.47 mM); Clear solution

    此方案可获得 ≥ 6.25 mg/mL (23.47 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例，取 100 μL 62.5 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在 Shanghai Jinpan Biotech Co Ltd 网站选购。
参考文献

  • [1]. Ningbo Gong, et al. Concomitant polymorphs of methoxyflavone (5-methyl-7-methoxyflavone). RSC Adv., 2016, 6, 38709-38715.

Scutellarin methyl ester(Synonyms: 灯盏花乙素甲酯； 野黄芩苷甲酯)

发表于由

天然产物 黄酮类 Flavonoids

Scutellarin methyl ester (Synonyms: 灯盏花乙素甲酯； 野黄芩苷甲酯)

Scutellarin methyl ester 是灯盏花素的一种成分, 灯盏花素是灯盏花中几种黄酮类化合物的粗提物。

Scutellarin methyl ester(Synonyms: 灯盏花乙素甲酯； 野黄芩苷甲酯)

Scutellarin methyl ester Chemical Structure

CAS No. : 119262-68-9

规格 价格 是否有货
5 mg ￥2690 询问价格 & 货期
10 mg ￥4570 询问价格 & 货期

* Please select Quantity before adding items.

生物活性

Scutellarin methyl ester is a constituent of Breviscapine which is a crude extract of several flavonoids of Erigeron breviscapus[1][2].

分子量

476.39

Formula

C22H20O12
CAS 号

119262-68-9
中文名称

灯盏花乙素甲酯； 野黄芩苷甲酯
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zhao M, et al. Structural identification of related substances in Breviscapine by UPLC-QTOF-MS. Zhongguo Zhong Yao Za Zhi. 2018 Jul;43(14):2872-2877.

    [2]. Gao J, et al. Therapeutic Effects of Breviscapine in Cardiovascular Diseases: A Review. Front Pharmacol. 2017 May 23;8:289.

5,7-Dimethoxyflavanone

发表于由

天然产物 黄酮类 Flavonoids

5,7-Dimethoxyflavanone  纯度: ≥99.0%

5,7-Dimethoxyflavanone 在 Ames 试验中对鼠伤寒 TA100 和 TA98 菌株的 MeIQ 诱变表现出较强的抗诱变活性，也能显著且剂量依赖性地抑制炎症介质:一氧化氮(NO)和细胞因子(TNF-α和IL-12)。

5,7-Dimethoxyflavanone

5,7-Dimethoxyflavanone Chemical Structure

CAS No. : 1277188-85-8

规格 价格 是否有货 数量
1 mg ￥2400 In-stock
5 mg ￥7200 In-stock
10 mg   询价  
50 mg   询价  

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5,7-Dimethoxyflavanone 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus

生物活性

5,7-Dimethoxyflavanone shows potent antimutagenic activity against MeIQ mutagenesis in Ames test using the S. typhimurium TA100 and TA98 strains[1]. And 5,7-Dimethoxyflavanone significantly and dose-dependently inhibits the inflammatory mediato

分子量

284.31

Formula

C17H16O4
CAS 号

1277188-85-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
参考文献

  • [1]. Okuno Y, Marumoto S, Miyazawa M. Antimutagenic activity of flavonoids from Sozuku. Nat Prod Res. 2019;33(6):862-865.

    [2]. Rao YK, Fang SH, Tzeng YM. Anti-inflammatory activities of flavonoids isolated from Caesalpinia pulcherrima. J Ethnopharmacol. 2005;100(3):249-253.

6”-O-Acetylglycitin

发表于由

天然产物 黄酮类 Flavonoids

6”-O-Acetylglycitin  纯度: 99.00%

6”-O-Acetylglycitin 6”-O-乙酰黄豆黄苷是一种乙酰基葡萄糖苷，大豆异黄酮异构体之一，其含量根据储存温度，包装条件和异黄酮异构体种类不同会显示出不同程度的含量降低。

6

6”-O-Acetylglycitin Chemical Structure

CAS No. : 134859-96-4

规格 价格 是否有货 数量
1 mg ￥1710 In-stock
5 mg ￥5140 In-stock
10 mg   询价  
50 mg   询价  

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6”-O-Acetylglycitin 相关产品

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  • Glycoside Compound Library
  • Medicine Food Homology Compound Library
  • Phenols Library
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  • Flavonoids Library
  • Food-Sourced Compound Library

生物活性

6”-O-Acetylglycitin, a acetyl glucoside, is one of the isoflavone isomer in soybeans, shows various extents of content reduction dependent on storage temperature, packaging condition, and its isoflavone isomer kind[1].

分子量

488.44

Formula

C24H24O11
CAS 号

134859-96-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献

  • [1]. Huang RY, et al. Stability of isoflavone isomers in steamed black soybeans and black soybean koji stored under different conditions. J Agric Food Chem. 2009 Mar 11;57(5):1927-32.

Vaccarin(Synonyms: 王不留行黄酮苷)

发表于由

天然产物 黄酮类 Flavonoids

Vaccarin (Synonyms: 王不留行黄酮苷) 纯度: 99.35%

Vaccarin是一种具有多种生物学功能的活性类黄酮糖苷。Vaccarin 显着促进伤口愈合以及伤口部位的内皮细胞和成纤维细胞增殖。Vaccarin 通过激活 AMPK 信号通路改善胰岛素抵抗和脂肪变性。

Vaccarin(Synonyms: 王不留行黄酮苷)

Vaccarin Chemical Structure

CAS No. : 53452-16-7

规格 价格 是否有货 数量
5 mg ￥800 In-stock
10 mg ￥1400 In-stock
20 mg ￥2300 In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Vaccarin 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Epigenetics Compound Library
  • Kinase Inhibitor Library
  • PI3K/Akt/mTOR Compound Library
  • Natural Product Library
  • Anti-Aging Compound Library
  • Antioxidants Compound Library
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  • Oxygen Sensing Compound Library
  • Phenols Library
  • Glycolysis Compound Library
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  • Anti-Pancreatic Cancer Compound Library
  • Anti-Cancer Metabolism Compound Library
  • Anti-Obesity Compound Library
  • Lipid Metabolism Compound Library
  • Glucose Metabolism Compound Library

生物活性

Vaccarin is an active flavonoid glycoside associated with various biological functions. Vaccarin significantly promote wound healing and endothelial cells and fibroblasts proliferation in the wound site. Vaccarin ameliorates insulin resistance and steatosis by activating the AMPK signaling pathway[1][2].

分子量

726.63

Formula

C32H38O19
CAS 号

53452-16-7
中文名称

王不留行黄酮苷
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶解性数据
In Vitro: 

DMSO : 125 mg/mL (172.03 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.3762 mL 6.8811 mL 13.7622 mL
5 mM 0.2752 mL 1.3762 mL 2.7524 mL
10 mM 0.1376 mL 0.6881 mL 1.3762 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂： 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (2.86 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (2.86 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂： 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (2.86 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (2.86 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
  • 3.

    请依序添加每种溶剂： 10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (2.86 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (2.86 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在 Shanghai Jinpan Biotech Co Ltd 网站选购。
参考文献

  • [1]. Lei Y, et al. Vaccarin ameliorates insulin resistance and steatosis by activating the AMPK signaling pathway. Eur J Pharmacol. 2019 May 15;851:13-24.

    [2]. Hou B,et al. Vaccarin hastens wound healing by promoting angiogenesis via activation of MAPK/ERK and PI3K/AKT signaling pathways in vivo. Acta Cir Bras. 2020 Feb 7;34(12):e201901202.

Artemitin(Synonyms: 艾黄素)

发表于由

天然产物 黄酮类 Flavonoids

Artemitin (Synonyms: 艾黄素) 纯度: 99.20%

Artemitin 是一种天然黄酮，存在于翼齿六棱菊中，具有抗氧化、抗炎、抗病毒作用。

Artemitin(Synonyms: 艾黄素)

Artemitin Chemical Structure

CAS No. : 479-90-3

规格 价格 是否有货 数量
5 mg ￥1190 In-stock
10 mg ￥2020 In-stock
20 mg ￥3430 In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Artemitin 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Anti-Infection Compound Library
  • Immunology/Inflammation Compound Library
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  • Phenols Library
  • Traditional Chinese Medicine Monomer Library
  • Flavonoids Library
  • Food-Sourced Compound Library

生物活性

Artemitin is a flavonol found in Laggera pterodonta (DC.) Benth., with antioxidative, anti-inflammatory, and antiviral activity[1].

分子量

388.37

Formula

C20H20O8
CAS 号

479-90-3
中文名称

艾黄素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶解性数据
In Vitro: 

DMSO : 50 mg/mL (128.74 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.5749 mL 12.8743 mL 25.7486 mL
5 mM 0.5150 mL 2.5749 mL 5.1497 mL
10 mM 0.2575 mL 1.2874 mL 2.5749 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Han X, et al. Development of an LC-MS/MS-based assay to determine artemitin in rat plasma and its application in a pharmacokinetic study. Biomed Chromatogr. 2018 Dec;32(12):e4356.

Loureiriol

发表于由

天然产物 黄酮类 Flavonoids

Loureiriol 

Loureiriol 是一种同型异黄酮类化合物，具有较弱的抗癌作用。

Loureiriol

Loureiriol Chemical Structure

CAS No. : 479195-44-3

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Loureiriol is a homoisoflavonoid with weak anticancer effects[1].

体外研究
(In Vitro)

Loureiriol has weak cytotoxicity, with cell inhibition of 15.27% and 25.09% against drug sensitive CCRF-CEM and drug resistant CEM/ADR5000 leukemia cells, respectively[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

302.28

Formula

C16H14O6
CAS 号

479195-44-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Vaderament-A.Nchiozem-Ngnitedem, et al. Two new flavonoids from Dracaena usambarensis Engl. Phytochemistry Letters (2020), 36, 80-85.

Chrysosplenetin(Synonyms: 猫眼草黄素)

发表于由

天然产物 黄酮类 Flavonoids

Chrysosplenetin (Synonyms: 猫眼草黄素) 纯度: 99.52%

Chrysosplenetin 是青蒿 (Artemisia annua) 和其他几种中草药中的多甲氧基化黄酮类化合物之一。 Chrysosplenetin 抑制P-gp 活性并逆转由青蒿素 (ART) 诱导的上调的 P-gp 和 MDR1 水平。 Chrysosplenetin 显着增强 ART 在大鼠血浆水平和抗疟疾功效，部分因为其对大鼠 CYP3A 的非竞争性抑制作用。

Chrysosplenetin(Synonyms: 猫眼草黄素)

Chrysosplenetin Chemical Structure

CAS No. : 603-56-5

规格 价格 是否有货 数量
5 mg ￥2970 In-stock
10 mg ￥5040 In-stock
20 mg ￥8570 In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Chrysosplenetin 相关产品

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  • Flavonoids Library
  • Food-Sourced Compound Library

生物活性

Chrysosplenetin is one of the polymethoxylated flavonoids in Artemisia annua L. (Compositae) and other several Chinese herbs. Chrysosplenetin inhibits P-gp activity and reverses the up-regulated P-gp and MDR1 levels induced by artemisinin (ART). Chrysosplenetin significantly augments the rat plasma level and anti-malarial efficacy of ART, partially due to the uncompetitive inhibition effect of Chrysosplenetin on rat CYP3A[1].

IC50 & Target[1]

CYP3A

 

分子量

374.34

Formula

C19H18O8
CAS 号

603-56-5
中文名称

猫眼草黄素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶解性数据
In Vitro: 

DMSO : 100 mg/mL (267.14 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.6714 mL 13.3568 mL 26.7137 mL
5 mM 0.5343 mL 2.6714 mL 5.3427 mL
10 mM 0.2671 mL 1.3357 mL 2.6714 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂： 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (6.68 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (6.68 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液

*以上所有助溶剂都可在 Shanghai Jinpan Biotech Co Ltd 网站选购。
参考文献

  • [1]. Ma L, et al. Chrysosplenetin inhibits artemisinin efflux in P-gp-over-expressing Caco-2 cells and reverses P-gp/MDR1 mRNA up-regulated expression induced by artemisinin in mouse small intestine. Pharm Biol. 2017 Dec;55(1):374-380.

5-O-Demethylnobiletin(Synonyms: 5-Demethylnobiletin)

发表于由

天然产物 黄酮类 Flavonoids

5-O-Demethylnobiletin (Synonyms: 5-Demethylnobiletin) 纯度: 99.93%

5-O-Demethylnobiletin (5-Demethylnobiletin) 5-O-去甲肾上腺素，一种从黄芪中分离出的多甲氧基黄酮，是 5-LOX 的直接抑制剂 (IC50=0.1 μM)，不影响 COX-2 的表达。5-O-Demethylnobiletin (5-Demethylnobiletin) 5-O-去甲肾上腺素具有抗炎活性，抑制大鼠中性粒细胞中白三烯 B (4)(LTB4) 的形成和人嗜中性粒细胞中弹性蛋白酶的释放，IC50 值为0.35 μM.

5-O-Demethylnobiletin(Synonyms: 5-Demethylnobiletin)

5-O-Demethylnobiletin Chemical Structure

CAS No. : 2174-59-6

规格 价格 是否有货 数量
5 mg ￥1580 In-stock
10 mg ￥2690 In-stock
20 mg ￥4570 In-stock
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100 mg   询价  

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5-O-Demethylnobiletin 相关产品

•相关化合物库:

  • Natural Product Library Plus
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  • Immunology/Inflammation Compound Library
  • Metabolism/Protease Compound Library
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  • Phenols Library
  • Flavonoids Library
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  • Food-Sourced Compound Library

生物活性

5-O-Demethylnobiletin (5-Demethylnobiletin), a polymethoxyflavone isolated from Sideritis tragoriganum, is a direct inhibition of 5-LOX (IC50=0.1 μM), without affecting the expression of COX-2. 5-O-Demethylnobiletin (5-Demethylnobiletin) has anti-inflammatory activity, inhibits leukotriene B (4)(LTB4) formation in rat neutrophils and elastase release in human neutrophils with an IC50 of 0.35 μM[1].

IC50 & Target[1]

LTC4

0.35 μM (IC50)

5-LOX

0.1 μM (IC50)

体外研究
(In Vitro)

5-O-Demethylnobiletin (5-demethylnobiletin) promotes neuritogenesis through the activation of MAPK/ERK-, PKC-, and PKA-dependent signaling pathways[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

388.37

Formula

C20H20O8
CAS 号

2174-59-6
中文名称

5-O-去甲肾上腺素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶解性数据
In Vitro: 

DMSO : 25 mg/mL (64.37 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.5749 mL 12.8743 mL 25.7486 mL
5 mM 0.5150 mL 2.5749 mL 5.1497 mL
10 mM 0.2575 mL 1.2874 mL 2.5749 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂： 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (6.44 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (6.44 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂： 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (6.44 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (6.44 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
*以上所有助溶剂都可在 Shanghai Jinpan Biotech Co Ltd 网站选购。
参考文献

  • [1]. Bas E, et al. Anti-inflammatory activity of 5-O-demethylnobiletin, a polymethoxyflavone isolated from Sideritis tragoriganum. Planta Med. 2006 Feb;72(2):136-42.

    [2]. Chiu SP, et al. Neurotrophic action of 5-hydroxylated polymethoxyflavones: 5-demethylnobiletin and gardenin A stimulate neuritogenesis in PC12 cells. J Agric Food Chem. 2013 Oct 2;61(39):9453-63.

3′,4′,5′,5,6,7-Hexamethoxyflavone

发表于由

天然产物 黄酮类 Flavonoids

3′,4′,5′,5,6,7-Hexamethoxyflavone 

3′,4′,5′,5,6,7-Hexamethoxyflavone 是一种具有抗原生动物活性的黄酮类化合物。3′,4′,5′,5,6,7-Hexamethoxyflavone 抑制 trypanosoma bruceirhodesiense，IC50 值为 21.3 μM (8.58 g/mL)。

3′,4′,5′,5,6,7-Hexamethoxyflavone

3′,4′,5′,5,6,7-Hexamethoxyflavone Chemical Structure

CAS No. : 29043-07-0

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

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生物活性

3′,4′,5′,5,6,7-Hexamethoxyflavone is a flavonoid with antiprotozoal activity. 3′,4′,5′,5,6,7-Hexamethoxyflavone inhibits trypanosoma bruceirhodesiense with IC50 of 21.3 μM (8.58 g/mL)[1].

分子量

402.39

Formula

C21H22O8
CAS 号

29043-07-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Nour AM, et al. The antiprotozoal activity of methylated flavonoids from Ageratum conyzoides L. J Ethnopharmacol. 2010;129(1):127-130.