RIPK2 品牌：Carna Bio

RIPK2

品牌：Carna Bio
CAS No.：
储存条件：-80℃
纯度：–

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
307-82923	–	5 ug	–	咨询	–	–

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* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

RIPK1-IN-12;

RIPK1-IN-12 是一种有效的 RIPK1 抑制剂，RIPK1-IN-12 能抑制人和小鼠细胞的坏死性凋亡，EC₅₀ 值分别为 1.6 和 2.9 nM.

RIPK1-IN-12 Chemical Structure

CAS No. : 2173556-92-6

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生物活性	RIPK1-IN-12 is a potent RIPK1 inhibitor. RIPK1-IN-12 inhibits necroptosis in both human and mouse cells, with EC₅₀ values of 1.6 and 2.9 nM, respectively^[1].
IC₅₀ Target	RIPK1^[1]
体外研究 (In Vitro)	RIPK1-IN-12 (Compound 58; 24 hours) demonstrates potent anti-necroptotic activity (EC₅₀=1.6 nM in HT-29 cells and EC₅₀= 2.9 nM in L929 cells)^[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	450.55
Formula	C₂₄H₂₆N₄O₃S
CAS 号	2173556-92-6
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Li Z, et al. Design, synthesis, and evaluation of potent RIPK1 inhibitors with in vivo anti-inflammatory activity. Eur J Med Chem. 2022, 228:114036.

品牌：Carna Bio
CAS No.：
储存条件：-80℃
纯度：–

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
301-82921	–	100 ug	–	咨询	–	–

* 干冰运输、大包装及大批量的产品需酌情添加运输费用