Fmoc-Gln(Trt)-Ser(psi(Me,Me)pro)-OH

发表于2022年8月11日由Whatman官网

Fmoc-Gln(Trt)-Ser(psi(Me,Me)pro)-OH;

Fmoc-Gln(Trt)-Ser(psi(Me,Me)pro)-OH 是一种二肽。

Fmoc-Gln(Trt)-Ser(psi(Me,Me)pro)-OH Chemical Structure

CAS No. : 1821378-64-6

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

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生物活性

Fmoc-Gln(Trt)-Ser(psi(Me,Me)pro)-OH is a dipeptide.

分子量

737.84

Formula

C₄₅H₄₃N₃O₇

CAS 号

1821378-64-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility

In Vitro:;

H₂O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

;	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3.;;Recommended solution:

Overall charge of peptide	Details
Negative (lt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, add NH₄OH (lt;50 μL). 3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

des-Gln14-Ghrelin TFA

发表于2022年7月16日由Whatman官网

des-Gln14-Ghrelin TFA;

des-Gln14-Ghrelin TFA 是生长激素促分泌受体的第二个内源性配体。des-Gln14-Ghrelin 可诱导 CHO-GHSR62 细胞中 [Ca²⁺]I 的上条，其 EC₅₀ 值为2.4 nM。

des-Gln14-Ghrelin TFA Chemical Structure

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

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生物活性	des-Gln14-Ghrelin TFA is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca²⁺]i in CHO-GHSR62 cells, with an EC₅₀ of 2.4 nM^[1].
分子量	3300.69
Formula	C₁₄₄H₂₃₈F₃N₄₃O₄₂
Sequence	Gly-Ser-{Oct-Ser}-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg
Sequence Shortening	GS-{Oct-Ser}-FLSPEHQKAQRKESKKPPAKLQPR
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. H Hosoda, et al. Purification and Characterization of Rat des-Gln14-Ghrelin, a Second Endogenous Ligand for the Growth Hormone Secretagogue Receptor. J Biol Chem. 2000 Jul 21;275(29):21995-2000.

Cyclo(Gly-Gln)

发表于2022年6月30日由Whatman官网

Cyclo(Gly-Gln);

Cyclo(Gly-Gln) 是一种环状二肽。

Cyclo(Gly-Gln) Chemical Structure

CAS No. : 52662-00-7

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

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生物活性

Cyclo(Gly-Gln) is a cyclic dipeptide^[1].

分子量

185.18

Formula

C₇H₁₁N₃O₃

CAS 号

52662-00-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility

In Vitro:;

H₂O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

;	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3.;;Recommended solution:

Overall charge of peptide	Details
Negative (lt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, add NH₄OH (lt;50 μL). 3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

参考文献

[1]. Takashi Mizuma, et al. Uptake of Cyclic Dipeptide by PEPT1 in Caco-2 Cells: Phenolic Hydroxyl Group of Substrate Enhances Affinity for PEPT1. J Pharm Pharmacol. 2002 Sep;54(9):1293-6.

des-Gln14-Ghrelin

发表于2022年6月20日由Whatman官网

des-Gln14-Ghrelin;

des-Gln14-Ghrelin 是生长激素促分泌受体的第二个内源性配体。des-Gln14-Ghrelin 可诱导 CHO-GHSR62 细胞中 [Ca²⁺]i 的上条，其 EC₅₀ 值为2.4 nM。

des-Gln14-Ghrelin Chemical Structure

CAS No. : 293735-04-3

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

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生物活性

des-Gln14-Ghrelin is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca²⁺]i in CHO-GHSR62 cells, with an EC₅₀ of 2.4 nM^[1].

分子量

3186.67

Formula

C₁₄₂H₂₃₇N₄₃O₄₀

CAS 号

293735-04-3

Sequence

Gly-Ser-{Oct-Ser}-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg

Sequence Shortening

GS-{Oct-Ser}-FLSPEHQKAQRKESKKPPAKLQPR

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility

In Vitro:;

H₂O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

;	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3.;;Recommended solution:

Overall charge of peptide	Details
Negative (lt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, add NH₄OH (lt;50 μL). 3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

参考文献

[1]. H Hosoda, et al. Purification and Characterization of Rat des-Gln14-Ghrelin, a Second Endogenous Ligand for the Growth Hormone Secretagogue Receptor. J Biol Chem. 2000 Jul 21;275(29):21995-2000.

Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2

发表于2022年6月20日由Whatman官网

Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2;

Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2 是血清稳定的，对神经细胞无毒的，可以选择性抑制tau的纤维化.

Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2 Chemical Structure

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

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生物活性	Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2 is serum stable, non-toxic to neuronal cells, and selectivity inhibits the fibrilization of tau over Aβ₄₂.
分子量	819.99
Formula	C₃₈H₆₅N₁₁O₉
Sequence Shortening	Ac-VQ-{Ile(N-NH2)}-V-{Tyr(N-NH2)}-K-NH2
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Makwana KM, et al. N-Amination Converts Amyloidogenic Tau Peptides into Soluble Antagonists of Cellular Seeding. ACS Chem Neurosci. 2021 Oct 20;12(20):3928-3938.

Fmoc-Gln(Trt)-Thr(psi(Me,Me)pro)-OH

发表于2022年6月20日由Whatman官网

Fmoc-Gln(Trt)-Thr(psi(Me,Me)pro)-OH;

Fmoc-Gln(Trt)-Thr(psi(Me,Me)pro)-OH 是一种二肽。

Fmoc-Gln(Trt)-Thr(psi(Me,Me)pro)-OH Chemical Structure

CAS No. : 1572725-72-4

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

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生物活性

Fmoc-Gln(Trt)-Thr(psi(Me,Me)pro)-OH is a dipeptide.

分子量

751.87

Formula

C₄₆H₄₅N₃O₇

CAS 号

1572725-72-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility

In Vitro:;

H₂O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

;	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3.;;Recommended solution:

Overall charge of peptide	Details
Negative (lt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, add NH₄OH (lt;50 μL). 3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

[Gln8]-C517 (LH-RH), chicken

发表于2022年4月29日由Whatman官网

[Gln8]-C517 (LH-RH), chicken; 纯度: 98.49%

[Gln8]-C517 (LH-RH), chicken 是一种禽类下丘脑肽，刺激垂体前叶释放促性腺激素，从而调节生殖功能。

[Gln8]-C517 (LH-RH), chicken Chemical Structure

CAS No. : 47922-48-5

规格	价格	是否有货	数量
5 mg	￥1000	In-stock
10 mg	￥1700	In-stock
50 mg	;	询价	;
100 mg	;	询价	;

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[Gln8]-C517 (LH-RH), chicken 相关产品

bull;相关化合物库:

Bioactive Compound Library Plus
Peptide Library

生物活性

[Gln8]-C517 (LH-RH), chicken is an avian hypothalamic peptide, which stimulates release of gonadotropins from anterior pituitary, thus regulating reproductive functions.

分子量

1154.23

Formula

C₅₄H₇₁N₁₅O₁₄

CAS 号

47922-48-5

Sequence

{pGLU}-His-Trp-Ser-Tyr-Gly-Leu-Gln-Pro-Gly

Sequence Shortening

{pGLU}-HWSYGLQPG

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-80deg;C	2 years
	-20deg;C	1 year
In solvent	-80deg;C	6 months
	-20deg;C	1 month

Solvent Solubility

In Vitro:;

H₂O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

;	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3.;;Recommended solution:

Overall charge of peptide	Details
Negative (lt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, add NH₄OH (lt;50 μL). 3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

参考文献

[1]. Maurer JA, et al. Luteinizing hormone-releasing hormone (LHRH) neurons maintained in hypothalamic slice explant cultures exhibit a rapid LHRH mRNA turnover rate. J Neurosci. 1997 Dec 15;17(24):9481-91.

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标签归档：gln

Fmoc-Gln(Trt)-Ser(psi(Me,Me)pro)-OH

des-Gln14-Ghrelin TFA

Cyclo(Gly-Gln)

des-Gln14-Ghrelin

Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2

Fmoc-Gln(Trt)-Thr(psi(Me,Me)pro)-OH

[Gln8]-C517 (LH-RH), chicken

[Gln8]-C517 (LH-RH), chicken 相关产品

bull;相关化合物库:

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