Astaxanthin, a red dietary carotenoid isolated from Haematococcus pluvialis, is a modulator of PPARγ and a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity[1]. Astaxanthin has potential in the study of various diseases, such as cancers and Parkinson’s disease, cardiovascular disease[2]. Due to its bright red colour, Astaxanthin could be used as a food colorant in animal feeds[3].
IC50 & Target[1]
PPARγ
Clinical Trial
分子量
596.84
Formula
C40H52O4
CAS 号
472-61-7
中文名称
虾青素
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
-20°C, protect from light, stored under nitrogen
*该产品在溶液状态不稳定,建议您现用现配,即刻使用。
溶解性数据
In Vitro:
DMSO : 2 mg/mL (3.35 mM; Need ultrasonic)
Acetone : < 1 mg/mL (insoluble)
*Astaxanthin is usually formulated as a suspension.
[1]. Yang Y, et al. Epigenetic CpG Methylation of the Promoter and Reactivation of the Expression of GSTP1 by Astaxanthin in Human Prostate LNCaP Cells. AAPS J. 2017 Mar;19(2):421-430.
[2]. Desheng Fu, et al. Effect of astaxanthin on retinal pigment epithelial cells in high glucose: an invitro study. Biomedical Research 2017; 28 (15): 6839-6843.
[3]. Rachel K Johnston, et al. Effects of astaxanthin on Brachionus manjavacas (Rotifera) population growth. Aquaculture Research. 2018;49:2278–2287.