标签归档：des

Angiotensin I [Des-Asp1] (Human) 品牌：Anygen

发表于由

Angiotensin I [Des-Asp1] (Human)

品牌：Anygen
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

302-36063

 – 0.5 mg – 咨询 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

[Sar0,D-F8,Des-R9]-Bradykinin 品牌：Anygen

发表于由

[Sar0,D-F8,Des-R9]-Bradykinin

品牌：Anygen
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

303-89441

 – 0.5 mg – 咨询 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

des-​Gln14-​Ghrelin TFA

发表于由

des-​Gln14-​Ghrelin TFA;

des-Gln14-Ghrelin TFA 是生长激素促分泌受体的第二个内源性配体。des-Gln14-Ghrelin 可诱导 CHO-GHSR62 细胞中 [Ca2+]I 的上条，其 EC50 值为2.4 nM。

des-​Gln14-​Ghrelin TFAamp;;

des-​Gln14-​Ghrelin TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

des-Gln14-Ghrelin TFA is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca2+]i in CHO-GHSR62 cells, with an EC50 of 2.4 nM[1].

分子量

3300.69

Formula

C144H238F3N43O42
Sequence

Gly-Ser-{Oct-Ser}-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg
Sequence Shortening

GS-{Oct-Ser}-FLSPEHQKAQRKESKKPPAKLQPR
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. H Hosoda, et al. Purification and Characterization of Rat des-Gln14-Ghrelin, a Second Endogenous Ligand for the Growth Hormone Secretagogue Receptor. J Biol Chem. 2000 Jul 21;275(29):21995-2000.

(Des-Br)-NPB-29 (Human) 人神经肽B-29 品牌：Anygen

发表于由

(Des-Br)-NPB-29 (Human)

人神经肽B-29

品牌：Anygen
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

303-91651

 – 0.5 mg – 咨询 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

[Des-His1,Glu9]-Glucagon amide

发表于由

[Des-His1,Glu9]-Glucagon amide;

[Des-His1,Glu9]-Glucagon amide 是一种有效的胰高血糖素受体的肽拮抗剂，pA2 值为 7.2。 [Des-His1,Glu9]-Glucagon amide 在糖尿病的发病机理研究中有用。

[Des-His1,Glu9]-Glucagon amideamp;;

[Des-His1,Glu9]-Glucagon amide Chemical Structure

CAS No. : 110084-95-2

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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[Des-His1,Glu9]-Glucagon amide 的其他形式现货产品:

[Des-His1,Glu9]-Glucagon amide TFA

生物活性

[Des-His1,Glu9]-Glucagon amide is a potent and peptide antagonist of the glucagon receptor, with a pA2 of 7.2. [Des-His1,Glu9]-Glucagon amide is potentially useful in the study of the pathogenesis of diabetes[1].

IC50 Target

glucagon receptor[1]
分子量

3358.65

Formula

C148H221N41O47S
CAS 号

110084-95-2
Sequence

Ser-Gln-Gly-Thr-Phe-Thr-Ser-Glu-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-NH2
Sequence Shortening

SQGTFTSEYSKYLDSRRAQDFVQWLMNT-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Unson CG, et, al. Biological activities of des-His1[Glu9]glucagon amide, a glucagon antagonist. Peptides. 1989 Nov; 10(6): 1171-7.

des-​Gln14-​Ghrelin

发表于由

des-​Gln14-​Ghrelin;

des-Gln14-Ghrelin 是生长激素促分泌受体的第二个内源性配体。des-Gln14-Ghrelin 可诱导 CHO-GHSR62 细胞中 [Ca2+]i 的上条，其 EC50 值为2.4 nM。

des-​Gln14-​Ghrelinamp;;

des-​Gln14-​Ghrelin Chemical Structure

CAS No. : 293735-04-3

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

des-Gln14-Ghrelin is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca2+]i in CHO-GHSR62 cells, with an EC50 of 2.4 nM[1].

分子量

3186.67

Formula

C142H237N43O40
CAS 号

293735-04-3
Sequence

Gly-Ser-{Oct-Ser}-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg
Sequence Shortening

GS-{Oct-Ser}-FLSPEHQKAQRKESKKPPAKLQPR
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. H Hosoda, et al. Purification and Characterization of Rat des-Gln14-Ghrelin, a Second Endogenous Ligand for the Growth Hormone Secretagogue Receptor. J Biol Chem. 2000 Jul 21;275(29):21995-2000.

[Des-Tyr1]-Met-Enkephalin

发表于由

[Des-Tyr1]-Met-Enkephalin;

[Des-Tyr1]-Met-Enkephalin 是一种四肽，是脑啡肽的降解产物。

[Des-Tyr1]-Met-Enkephalinamp;;

[Des-Tyr1]-Met-Enkephalin Chemical Structure

CAS No. : 61370-88-5

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

[Des-Tyr1]-Met-Enkephalin, a tetrapeptide, is a degradationproduct of enkephalins[1].

体外研究
(In Vitro)

Tetrapeptide H-gily-gly-phe-met-oh shows very littleactivity using the mouse[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

410.49

Formula

C18H26N4O5S
CAS 号

61370-88-5
Sequence Shortening

GGFM
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. J M Hambrook, et al. Mode of deactivation of the enkephalins by rat and human plasma and rat brain homogenates. Nature. 1976 Aug 26;262(5571):782-3.