分类目录归档：天然产物醌类

天然产物醌类

Dihydroevocarpine

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天然产物醌类Quinones

Dihydroevocarpine 

Dihydroevocarpine 通过抑制 mTORC1/2 活性诱导急性髓系白血病细胞毒性。

Dihydroevocarpine

Dihydroevocarpine Chemical Structure

CAS No. : 15266-35-0

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生物活性

Dihydroevocarpine induces cytotoxicity in acute myeloid leukemia via suppressing the mTORC1/2 activity[1].

分子量

341.53

Formula

C23H35NO
CAS 号

15266-35-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zhang S, et al. Targeting of mTORC1/2 by dihydroevocarpine induces cytotoxicity in acute myeloid leukemia. J Cell Physiol. 2019;234(8):13032-13041.

Nidurufin

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天然产物醌类Quinones

Nidurufin 

Nidurufin 是一种有效的细胞周期抑制剂，具有抗肿瘤活性。Nidurufin 以浓度和时间依赖性的方式诱导 K562 细胞系G2/M过渡期的体外细胞周期阻滞，IC50=12.6μM。

Nidurufin

Nidurufin Chemical Structure

CAS No. : 28458-23-3

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生物活性

Nidurufin is a potent cell cycle inhibitor with antitumor activity.Nidurufin induces in vitro cell cycle arrest at G2/M transition in the K562 cell line in a concentration and time dependent manner(IC50=12.6 μM)[1].

分子量

384.34

Formula

C20H16O8
CAS 号

28458-23-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Hong Ren, et al.Nidurufin as a new cell cycle inhibitor from marine-derived fungus Penicillium flavidorsum SHK1-27. Arch Pharm Res. 2011 Jun;34(6):901-5.

Isoeleutherin(Synonyms: 异红葱乙素)

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天然产物醌类Quinones

Isoeleutherin (Synonyms: 异红葱乙素)

Isoeleutherin 是从 Merr. Et Heyne 中分离得到的萘酚类衍生物，具有抗真菌、抗病毒和抗肿瘤活性。Isoeleutherin 在 T 辅助细胞介导的免疫反应选择性调节中起重要作用。

Isoeleutherin(Synonyms: 异红葱乙素)

Isoeleutherin Chemical Structure

CAS No. : 1078723-14-4

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1 mg ￥1600 询问价格 & 货期

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生物活性

Isoeleutherin is a naphthopyran derivative isolated from E. americana Merr. Et Heyne with anti-fungal, anti-viral, and anti-tumor activities. Isoeleutherin plays an important role in selective modulation of T helper cell-mediated immune responses[1].

分子量

272.30

Formula

C16H16O4
CAS 号

1078723-14-4
中文名称

异红葱乙素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Francesca R Gallo, et al. Polyketides from Eleutherine bulbosa. Nat Prod Res. 2010 Oct;24(16):1578-86.

Gambogellic acid

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天然产物醌类Quinones

Gambogellic acid 

Gambogellic acid 是从加工过的藤黄中分离得到的氧杂蒽酮类化合物，具有抗肿瘤活性。

Gambogellic acid

Gambogellic acid Chemical Structure

CAS No. : 173867-04-4

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5 mg ￥2690 询问价格 & 货期
10 mg ￥4570 询问价格 & 货期

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生物活性

Gambogellic acid is an xanthone isolated from the processed gamboge, with antitumor activity[1].

分子量

628.75

Formula

C38H44O8
CAS 号

173867-04-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Dong B, et al. Two new xanthone epimers from the processed gamboge. Nat Prod Res. 2017 Apr;31(7):817-821.

Xanthopurpurin(Synonyms: Purpuroxanthin)

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天然产物醌类Quinones

Xanthopurpurin (Synonyms: Purpuroxanthin) 纯度: 97.68%

Xanthopurpurin 是从 Rubia akane 根茎中分离的得到的一种蒽醌苷，主要对胶原诱导的血小板聚集有较强的抑制作用。

Xanthopurpurin(Synonyms: Purpuroxanthin)

Xanthopurpurin Chemical Structure

CAS No. : 518-83-2

规格 价格 是否有货 数量
1 mg ￥3800 In-stock
5 mg ￥11500 In-stock
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Xanthopurpurin 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus

生物活性

Xanthopurpurin, an anthraquinone glycoside, isolated from the roots of Rubia akane, shows mainly strong inhibition of collagen-induced platelet aggregation[1].

分子量

240.21

Formula

C14H8O4
CAS 号

518-83-2
中文名称

茜草红素；黄嘌呤红素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献

  • [1]. M I Chung, et al. Antiplatelet constituents of formosan Rubia akane. J Nat Prod. 1994 Feb;57(2):313-6.

Huanglongmycin N

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天然产物醌类Quinones

Huanglongmycin N 

Huanglongmycin N 是一种 DNA 拓扑异构酶 I 抑制剂（EC50 = 14 μM）。

Huanglongmycin N

Huanglongmycin N Chemical Structure

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生物活性

Huanglongmycin N is a DNA topoisomerase I inhibitor (EC50 = 14 μM).

IC50 & Target

Topoisomerase I

14 μM (EC50)

分子量

324.33

Formula

C19H16O5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zhu S, et al. Discovery of a DNA Topoisomerase I Inhibitor Huanglongmycin N and Its Congeners from Streptomyces sp. CB09001. J Org Chem. 2021 Dec 3;86(23):16675-16683.

6-Ethyl-2,7-dimethoxyjuglone

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天然产物醌类Quinones

6-Ethyl-2,7-dimethoxyjuglone 

6-Ethyl-2,7-dimethoxyjuglone 是一种从淡水真菌中分离出来的代谢物。

6-Ethyl-2,7-dimethoxyjuglone

6-Ethyl-2,7-dimethoxyjuglone Chemical Structure

CAS No. : 15254-86-1

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生物活性

6-Ethyl-2,7-dimethoxyjuglone is a metabolite isolated from freshwater fungi[1].

分子量

262.26

Formula

C14H14O5
CAS 号

15254-86-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Howe R, et al. 6-ethyl-5-hydroxy-2,7-dimethoxynaphthoquinone, a metabolite of Hendersonula toruloidea Nattrass. Experientia. 1969;25(5):474.

Cynodontin

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天然产物醌类Quinones

Cynodontin 

Cynodontin 是Helminthosporium cynodontis Marignoni 和Helminthosporium euchlaenae Zimmermann 的代谢产物。

Cynodontin

Cynodontin Chemical Structure

CAS No. : 476-43-7

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生物活性

Cynodontin is a metabolic product of Helminthosporium cynodontis Marignoni and Helminthosporium euchlaenae Zimmermann[1].

分子量

286.24

Formula

C15H10O6
CAS 号

476-43-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Raistrick H, et al. Studies in the biochemistry of micro-organisms: Cynodontin (1:4:5:8-tetrahydroxy-2-methylanthraquinone), a metabolic product of Helminthosporium cynodontis Marignoni and Helminthosporium euchlaenae Zimmermann. Biochem J. 1933;27(4):1170-1175.

3-Hydroxymorindone

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天然产物醌类Quinones

3-Hydroxymorindone 

3-Hydroxymorindone 是一种蒽醌类化合物和色素。

3-Hydroxymorindone

3-Hydroxymorindone Chemical Structure

CAS No. : 80368-74-7

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生物活性

3-Hydroxymorindone is an anthraquinone and a pigment[1][2].

分子量

286.24

Formula

C15H10O6
CAS 号

80368-74-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zhao F, et al. Zhongguo Zhong Yao Za Zhi. 2011;36(21):2980-2986.

    [2]. A.K. Prusty, et al, Colourimetric analysis and antimicrobial study of natural dyes and dyed silk, Journal of Cleaner Production, Volume 18, Issues 16–17, 2010, Pages 1750-1756, ISSN 0959-6526.

8-Methyl Chrysophanol(Synonyms: Chrysophanol 8-methyl ether)

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天然产物醌类Quinones

8-Methyl Chrysophanol (Synonyms: Chrysophanol 8-methyl ether)

8-Methyl Chrysophanol 是从Senna macranth 树皮中分离得到的一种蒽醌。

8-Methyl Chrysophanol(Synonyms: Chrysophanol 8-methyl ether)

8-Methyl Chrysophanol Chemical Structure

CAS No. : 3300-25-2

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1 mg ￥1300 询问价格 & 货期

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生物活性

8-Methyl Chrysophanol is an anthraquinone isolated from the bark of Senna macranth[1].

分子量

268.26

Formula

C16H12O4
CAS 号

3300-25-2
中文名称

8-甲基大黄酚
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Alexsandro Branco, et al. Anthraquinones from the bark of Senna macranthera. An Acad Bras Cienc. 2011 Dec;83(4):1159-64.