天然产物 黄酮类 Flavonoids
Glabrol (Synonyms: 光甘草醇) 纯度: 99.95%
Glabrol (Compound 1) 是从甘草根的乙醇提取物中分离得到的一种异戊二烯类黄酮,是一种有效且非竞争性的 ACAT (酰基辅酶 A:胆固醇酰基转移酶)抑制剂,对大鼠肝脏微粒体 ACAT 的 IC50 值为 24.6 μM。
Glabrol Chemical Structure
CAS No. : 59870-65-4
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥3030 | In-stock | |
10 mg | ¥5140 | In-stock | |
50 mg | 询价 | ||
100 mg | 询价 |
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Glabrol 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Metabolism/Protease Compound Library
- Natural Product Library
- Anti-Cardiovascular Disease Compound Library
- Medicine Food Homology Compound Library
- Phenols Library
- Traditional Chinese Medicine Monomer Library
- Flavonoids Library
- Lipid Metabolism Compound Library
生物活性 |
Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC50 value of 24.6 μM for rat liver microsomal ACAT activity[1]. |
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IC50 & Target[1] |
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体外研究 (In Vitro) |
Glabrol (Compound 1) decreases cholesteryl ester formation with an IC50 value of 26.0 μM in HepG2 cells[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
392.49 |
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Formula |
C25H28O4 |
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CAS 号 |
59870-65-4 |
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中文名称 |
光甘草醇 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (254.78 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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